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心血管疾病,特别是动脉粥样硬化心脏病和中风,在美国是致命的疾病。流行病学调查和临床观察表明:体育锻炼延迟或减缓冠状动脉粥样硬化的出现和发展。最近,体育锻炼、脂蛋白胆固醇与冠心病(CHD)之间的相互关系引起相当大的重视。提高高密度脂蛋白—胆固醇(HDL-C)能大大地减少冠心病的死亡率。体育锻炼虽然能增加血浆HDL—C,但很少人在控制已知的种各影响因素,像食物、脂肪量、吸烟、饮酒等来研究体育锻炼对HDL-C的影响。Haskell等人的试验中,虽然控制了年龄,身体指数,饮酒和吸烟、发现强度体育锻炼能提高HDL-C,但没有控制食物。
Cardiovascular diseases, especially atherosclerotic heart disease and stroke, are fatal diseases in the United States. Epidemiological investigation and clinical observation show that physical exercise delays or slows the appearance and development of coronary atherosclerosis. Recently, physical exercise, lipoprotein cholesterol and coronary heart disease (CHD) between the cause of considerable attention. Increasing high-density lipoprotein-cholesterol (HDL-C) can greatly reduce the mortality of coronary heart disease. Although physical exercise can increase plasma HDL-C, few people study the influence of physical exercise on HDL-C by controlling various known factors such as food, fat mass, smoking, drinking and so on. In Haskell et al’s trial, despite controlling for age, body mass index, alcohol consumption and smoking, it was found that intensive physical activity increased HDL-C but did not control food.