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目的通过流行病学调查,了解新疆哈萨克族代谢综合征(MS)的患病情况,比较美国国家胆固醇教育计划成年人治疗方案第三次报告(ATPⅢ)、国际糖尿病联盟(IDF)和中华医学会糖尿病学分会(CDS)建议的MS诊断标准在哈萨克族人群中应用的差异。方法对新疆地区2 219例哈萨克族居民进行横断面调查,根据3种诊断标准分别计算MS的患病率,分析不同诊断标准下MS异常组分及危险因素聚集的检出情况,比较3种诊断标准在哈萨克族人群中的一致性。结果 3种诊断标准的患病率(标准化患病率)分别为23.21%(21.29%)、23.88%(21.96%)和18.21%(16.65%)。3种标准对MS患者3个以上危险因素聚集的检出率分别为100.00%、96.23%和91.34%,其检出率比较差异有统计学意义(χ2=46.534,P=0.000)。3种诊断标准在哈萨克人群中应用的一致性两两比较,ATPⅢ标准与IDF标准的一致性较好(一致率为0.9878,Youden指数为0.9568,Kappa值为0.9662),CDS标准与另外两种标准(ATPⅢ和IDF)的一致性不高。结论 3种MS诊断标准在新疆哈萨克族人群中应用时,获得的患病率、危险因素聚集情况和一致性差异较大,IDF标准检出率最高,ATPⅢ标准对危险因素聚集检出率最高,且两者一致性较好,优于CDS标准。
Objective To understand the prevalence of metabolic syndrome (MS) in Kazak in Xinjiang through epidemiological investigation. To compare the ATP III, Adult Diabetes Federation (IDF) and Chinese Medical Association Differences in MS diagnostic criteria recommended by the Diabetes Unit (CDS) in the Kazakh population. Methods A total of 2 219 Kazakh residents in Xinjiang were investigated by cross-sectional survey. The prevalence of MS was calculated according to the three diagnostic criteria. The detection of MS abnormalities and aggregation of risk factors under different diagnostic criteria were analyzed. Consistency of standards among Kazakh ethnic groups. Results The prevalences (standardized prevalence) of the three diagnostic criteria were 23.21% (21.29%), 23.88% (21.96%) and 18.21% (16.65%), respectively. The detection rates of three kinds of risk factors in three kinds of MS patients were 100.00%, 96.23% and 91.34%, respectively. The detection rates were statistically significant (χ2 = 46.534, P = 0.000). The consistency of the three diagnostic criteria used in the Kazakh population was better in all pairs of ATP3 standards and IDF standards (the agreement rate was 0.9878, the Youden index was 0.9568, and the Kappa value was 0.9662). The CDS standard and the other two standards (ATP III and IDF) is not very consistent. Conclusion The diagnostic criteria of three kinds of MS in Xinjiang Kazak population, the prevalence of access, the risk of aggregation and consistency of the larger differences, IDF standard highest detection rate, ATP Ⅲ standard for the highest risk of aggregation of the highest detection rate, And the consistency between the two is better than the CDS standard.