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关节疾患是老年人病残的主要原因。由于大量新抗关节炎药物问世,使老年关节炎治疗有多种药物可供选择。关节炎病人常同时患有其它疾患,老年人更甚。因此,医生不仅要考虑药物的疗效及其毒性,而且还必须考虑药物与药物的相互作用和由于肝代谢和肾功能减退所引起的副作用增加。老年人的关节疾患老年人关节炎的最常见类型是骨关节炎。Kellgren和Lawrence指出55～64岁的人群中,虽然仅有12～20%患关节痛,但87%女性和83%男性的X线照片证实有骨关节炎。亦有作者指出,临床症状的出现与照片变化的严重程度显著相关。
Joint disease is the main reason for the elderly disabled. Due to the advent of a large number of new anti-arthritic drugs, there are a variety of medications available for the treatment of senile arthritis. Arthritis patients often suffer from other disorders, the elderly even worse. Therefore, physicians must consider not only the efficacy of the drug and its toxicity, but also the drug-drug interaction and the increased side effects due to liver metabolism and renal dysfunction. Arthralgia in the Elderly The most common type of arthritis in the elderly is osteoarthritis. Kellgren and Lawrence point out that although only 12-20% of people aged 55-64 suffer from arthralgia, radiographic evidence of osteoarthritis was found in 87% of women and 83% of men. Some authors also point out that the appearance of clinical symptoms is significantly related to the severity of the changes in the photos.