比较容易分离到金黄色葡萄球菌的妇产科疾病有外性器感染、创伤感染、产褥乳腺炎、新生儿感染(皮肤化脓性疾病等)。妇产科领域的内性器感染即盆腔内感染所分离的葡萄球菌与20年前比正在不断减少,然而近几年自从第3代头孢类抗菌素出现以后,人们开始发现含有本菌的革兰氏阳性球菌(GPC)有增加的倾向。但是从性器官感染总体来看,与其他科相比,可以说由MRSA感染的机率并不大。MRSA的抗药机理在于作用点的改变,由于对β-内酰胺类的低亲和性的青霉素结合蛋白PBP_2的产生,不只对二甲氧基苯青霉素,而且表现了抗所有的β-内酰胺类、很多的氨基甙类和大环内酯类抗菌素的耐药性。一、从妇产科感染分离的葡萄球菌和MRSA 1986～1989年盆腔内感染(子宫内感染、附件脓肿)、外性器感染(Bartholin氏腺脓肿、外阴脓肿)及创伤感染的分离菌,继需氧性革阴氏阴性杆菌之后,需氧性革兰氏阳性球菌和厌氧性菌(球菌、杆菌)几乎占相同的比例;但近年来厌氧菌多少有减少倾向。革兰 Obstetric and gynecological diseases that are more likely to be isolated from Staphylococcus aureus include external infection, traumatic infection, puerperal mastitis, neonatal infection (cutaneous purulent disease, etc.). In the field of obstetrics and gynecology infertility, ie staphylococcus aureus isolated from pelvic infection and 20 years ago than the declining, however, in recent years since the third generation of cephalosporin antibiotics appear, people began to find that the bacteria containing Gram Positive cocci (GPC) tends to increase. However, from the overall point of view of sexual organ infection, compared with other families, it can be said that the risk of MRSA infection is not large. The mechanism of MRSA resistance lies in the change of action point. Due to the low affinity β-lactam penicillin-binding protein PBP_2 production, not only for methicillin, but also showed resistance to all β-lactams Class, a lot of aminoglycosides and macrolide antibiotic resistance. First, staphylococcus aureus and MRSA isolated from the obstetrics and gynecology infection 1986 to 1989 pelvic infection (intrauterine infection, attachment abscess), external sexual infection (Bartholin’s gland abscess, vulvar abscess) and traumatic infections isolated bacteria, following the need Aerobic gram-negative bacilli, the aerobic gram-positive cocci and anaerobic bacteria (cocci, bacilli) accounted for almost the same proportion; but in recent years, the number of anaerobic bacteria tend to decrease. Gram