慢性移植肾功能不全是大多数移植肾失功的前奏,尽管新型免疫抑制剂及预防感染措施的应用,使得急性移植肾丢失显著下降,但是远期移植肾丢失并未改善[1],当前肾移植患者面对的主要危险因素为:因心血管疾病、恶性肿瘤、感染导致死亡和慢性移植肾功能不全导致移植肾丢失[2]。本文主 Chronic graft renal insufficiency is the prelude to most graft failures, and despite the new immunosuppressive agents and the use of measures to prevent infection, there is a significant loss of acute graft loss, but the long-term graft loss has not improved [1], and the current kidney Transplantation patients face the main risk factors are: due to cardiovascular disease, cancer, infection caused by death and chronic renal allograft lead to renal graft loss [2]. This article main