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目的对比分析紫杉醇与5-氟尿嘧啶治疗晚期食道癌的临床疗效。方法将我院收治的54例晚期食道癌患者实行分组研究,27例研究组采用紫杉醇与顺铂治疗,27例对照组采用5-氟尿嘧啶与顺铂治疗。结果研究组治疗的总有效率为88.89%,病灶缓解情况好,优于对照组的66.67%,二者组间比较P<0.05。结论采用紫杉醇与顺铂能有效缓解晚期食道癌患者的病灶,说明紫杉醇较5-氟尿嘧啶具备较高疗效。
Objective To compare the clinical efficacy of paclitaxel and 5-fluorouracil in the treatment of advanced esophageal cancer. Methods A total of 54 patients with advanced esophageal cancer admitted to our hospital were divided into two groups: 27 in the study group treated with paclitaxel and cisplatin, and 27 in the control group treated with 5-fluorouracil and cisplatin. Results The total effective rate of the study group was 88.89%, and the remission rate of the lesion was better than that of the control group (66.67%, P <0.05). Conclusion Paclitaxel and cisplatin can effectively alleviate the lesions of patients with advanced esophageal cancer, indicating that paclitaxel has a higher efficacy than 5-fluorouracil.