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目的研究抗苗勒管激素应用于卵巢储备功能早期预测工作中发挥的作用。方法选择2014年8月-2015年8月医院101例经血清清抗苗勒氏管激素检测确认为卵巢储备功能弱化引发不孕的患者,根据促排卵方式的差异将其划分为对照组50例和研究组51例,对照组在没有接受治疗的情况下直接进行促排卵,研究组接受人工周期治疗后再给予促排卵,对比2种促排卵方式的应用效果。结果研究组接受治疗后,其周期妊娠率为20.9%,明显高于对照组的9.7%差异有统计学意义(P<0.05);研究组临床妊娠率为35.3%,明显高于对照组的14.0%差异有统计学意义(P<0.05);研究组接受治疗后的AMH水平为2.92±0.39g/ml,明显优于治疗前的1.02±0.11 ng/m差异有统计学意义l(P<0.05)。结论针对卵巢储备功能弱化患者,选择抗苗勒管激素早期检测方法进行预测能够取得良好应用效果。
Objective To study the role of anti-Mullerian hormone in the early prediction of ovarian reserve. Methods From August 2014 to August 2015, 101 patients with serum anti-Müllerian hormone test in our hospital were identified as ovarian reserve weakening and infertility patients. According to the difference of ovulation induction method, they were divided into control group (n = 50) And study group of 51 cases, the control group in the absence of treatment of ovulation directly, the study group received artificial cycle treatment and then give ovulation, compared with two kinds of ovulation induction effect. Results The pregnancy rate of the study group after treatment was 20.9%, which was significantly higher than that of the control group (9.7%) (P <0.05). The clinical pregnancy rate in the study group was 35.3%, which was significantly higher than that in the control group (P <0.05). The level of AMH in study group was 2.92 ± 0.39g / ml, which was significantly better than 1.02 ± 0.11ng / m before treatment (P <0.05), the difference was statistically significant ). Conclusion For the patients with weakened ovarian reserve, the selection of anti-Mullerian hormone early detection method to predict can achieve good results.