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目的:介绍本单位对巨细胞病毒(CMV)感染的诊断和治疗体会。方法:1996年5月至1997年5月我院共做肾移植85例,其中7例发生CMV感染,诊断主要依据发热、肺炎、神经根炎及视网膜炎等。实验室检查主要用PCR方法测血、尿及眼分泌物中的CMV-DNA。胸片显示肺纹理增加。治疗主要用更昔洛韦,疗程10~24天。结果:7例中3例治愈,1例因CMV感染诱发慢性排异反应,行移植肾切除,另3例均死于严重的肺炎。结论:肾移植术后CMV感染应早期诊断及时治疗。
Objective: To introduce the unit diagnosis and treatment of cytomegalovirus (CMV) infection. Methods: May 1996 to May 1997 in our hospital a total of 85 cases of kidney transplantation, of which 7 cases of CMV infection, the diagnosis is mainly based on fever, pneumonia, radiculitis and retinitis. Laboratory tests mainly use the PCR method to measure CMV-DNA in blood, urine and eye secretions. Chest radiograph shows increased lung texture. Treatment with ganciclovir, treatment of 10 to 24 days. Results: Of the 7 cases, 3 cases were cured and 1 case was induced by CMV infection. Chronic rejection was performed. All three cases died of severe pneumonia. Conclusion: CMV infection after renal transplantation should be diagnosed and treated promptly.