先天性巨结肠症(以下简称巨结肠)(Hirschsprung′s)报道于1886年,近百年来,该病的诊断方法不断地改进,现概括为以下几种。1.直肠造影证明肠管狭窄段和继发扩张段。2.直肠肌层病理证明神经节细胞缺少。3.直肠肛门测压证明直肠肛门压力上升和肛门松弛反射消失。4.吸取直肠粘膜组织进行化学检查,证明直肠粘膜内 Hirschsprung’s (Hirschsprung’s) was reported in 1886, the diagnosis of the disease has been continuously improved over the past century, are summarized as the following. 1. Rectal angiography proved intestinal stenosis and secondary expansion. Rectal muscle pathology shows lack of ganglion cells. 3. Rectal anal manometry proves anal rectal pressure rise and anal relaxation reflex disappears. 4. Absorb the rectal mucosal tissue for chemical examination to prove that the rectal mucosa