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目的:探讨胰岛素样生长因子(IGF-1)及胰岛素样生长因子结合蛋(IGF-BP3)与异位妊娠的关系。方法:采用放射免疫法对早孕和输卵管妊娠患者血清中IGF-1和IGF-BP3的含量进行检测。结果:输卵管妊娠患者血清中IGF-1和IGF-BP3的含量低于早孕患者(P<0.05),差异显著。结论:IGF-1和IGF-BP3含量与异位妊娠密切相关,降低IGF为治疗异位妊娠开辟新的思路。
Objective: To investigate the relationship between insulin-like growth factor (IGF-1) and insulin-like growth factor binding protein (IGF-BP3) and ectopic pregnancy. Methods: The levels of IGF-1 and IGF-BP3 in serum of patients with early pregnancy and tubal pregnancy were detected by radioimmunoassay. Results: The serum levels of IGF-1 and IGF-BP3 in patients with tubal pregnancy were significantly lower than those in early pregnancy (P <0.05). Conclusion: The levels of IGF-1 and IGF-BP3 are closely related to ectopic pregnancy, and the reduction of IGF is a new way to treat ectopic pregnancy.