rotenone相关论文
Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in
We have previously shown that roflupram (ROF) protects against MPP+-induced neuronal damage in models of Parkinson\'s ......
急性肾损伤（acute kidney injury,AKI）是指缺血缺氧、感染、药物等各种原因导致的肾功能急剧恶化,从而引起全身多系统症状的一组严重......
Effects of the soil under Tephrosia vogelii on workers behavior of red imported fire ant ,Solenopsis
The objective of this study is to define the effects of Tephrosia vogelii (T.vogelii)soil on the red imported fire ant (......
Subcutaneous rotenone exposure causes selective dopaminergic degeneration and behavioral alterations
The systemic rotenone model of PD accurately replicates many aspects of the pathology of human PD.However,the major limi......
Neuroprotective effects of plant extracts against the neurotoxicity induced by rotenone, a mitochond
Aim: Rotenone, an inhibitor of mitochondnal complex Ⅰ, has been widely regarded as a neurotoxin because it induces a Pa......
Rotenone inhibits mTOR signaling by induction of reactive oxygen species leading to apoptosis of neu
Rotenone,an inhibitor of the mitochondrial electron transport chain complex,may induce neuronal apoptosis contributing t......
Baicalein causes alternation in dopamine metabolism in PC12 cells by inhibiting the expression of CO
Aim Baicalein is the major flavonoid obtained from the Scutellaria root.Our previous studies have demonstrated that baic......
Parkinsons disease (PD) is a typical neurodegenerative disorder that is symbolized by loss of dopaminergic neurons and m......
Rotenone induction of ROS inhibits mTOR-mediated S6K1 and 4E-BP1 pathways, leading to neuronal apopt
Rotenone,a common pesticide and inhibitor of mitochondrial complex I,induces loss of dopaminergic neurons and consequent......
Expression and release of microglial proinflammatory cytokine IL-6 and the effect of CysLT1R antagon
Objective: To determine whether the neurotoxin rotenone induces expression and release ofmicroglial proinflammatory cyto......
Experimental study of ginseng Rb fraction, Levodopa and their combination in the treatment of Parkin
Aim of study:Parkinsons disease (PD) is the second most common chronic neurodegenerative disorder,after Alzheimers disea......
Subcutaneous administration of rotenone has recently attracted attention because of its convenience,simplicity and effic......
A method for simultaneous determination of residuals of four pesticides, which are simazine, carboxin, diflubenzuron and......
Quantitative optical measurement of mitochondrial superoxide dynamics in pulmonary artery endothelia
Reactive oxygen species (ROS) play a vital role in cell signaling and redox regulation, but when present in excess, lead......
Novel compound FLZ alleviates rotenone-induced Parkinson disease model by sup⁃pressing TLR4/MyD88/NF
OBJECTIVES Parkinson disease(PD)is the second most common neurodegener⁃ative disease,but none of the current treatments......
An accurate and simple method of determining rotenone in eggplant was developed by High performance liquid chromatog......
The low insecticidal activity of rotenone against Spodoptera litura has been studied while its mechanism was not.To ......
Background:It is environmental to use botanical insecticides to control red imported fire (RIFA), Solenopsisinvicta.......
Rotenone has been used for many years in agriculture, but the dissipation and bioactivity of rotenone in different c......
Effect of rifampicin pre- and post-treatment on rotenone-induced dopaminergic neuronal apoptosis and
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Neurons are the most extensive and polarized cells that display a unique single long axon and multiple dendrites, which ......
Preliminary optimization of a Chinese herbal medicine formula based on the neuroprotective effects i
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目的研究芍药苷对鱼藤酮诱导人神经瘤母细胞（SH-SY5Y细胞）凋亡及线粒体损伤的保护作用。方法待细胞贴壁生长汇合度达到70%80%时,将细......
Objective: To investigate the effect of the prostaglandin El analogue misoprostol on oxidative stress and neurodegeratio......
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目的 :探讨血管紧张素Ⅱ(angiotensinⅡ,AngⅡ)对多巴胺能细胞损伤的影响及其机制。方法 :体外培养CATH.a细胞,鱼藤酮和(或)AngⅡ......
Multiple studies implicate iron accumulation in the substantia nigra in the degeneration of dopaminergic neurons in Park......
目的研究长期低剂量皮下注射鱼藤酮制作Lew is大鼠帕金森病模型.方法Lew is大鼠随机分为正常对照组和模型组,以1.0 mg.kg-1.d-1的......
目的在鱼藤酮处理BV-2小胶质细胞后,观测细胞中Drosha蛋白水平的变化以及相关炎症因子的表达改变。方法在不同浓度及时间的鱼藤酮......
帕金森病(Parkinson’s disease，PD、)是好发于老年人的神经退行性疾病，主要表现为静止性震颤，运动迟缓和肌强直，严重影响人类的健康和......
帕金森病（Parkinson’s disease，PD）是常见的中枢神经系统慢性退行性疾病，临床主要表现为静止性震颤、运动徐缓、肌僵直以及平衡功能失......
Aim: To study the role of dopamine (DA) in rotenone-induced neurotoxicity in PC12 cells. Methods: Cell viability was ass......
20C, a bibenzyl compound isolated from Gastrodia elata, protects PC12 cells against rotenone-induced
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Olanzapine is an antipsychotic drug used to treat patients with schizophrenia due to its lower incidence of extrapyramid......
Anti-proliferative potential of sodium thiosulfate against HT 29 human colon cancer cells with augme
Objective: To compare the anti-proliferative effect of sodium thiosulfate on human colorectal cancer cells (HT-29) and n......
目的构建SD大鼠鱼藤酮慢性中毒模型,同时对SD大鼠组织标本(脑组织和肝脏)进行线粒体DNA突变的初步探索,为后续实验提供线索。方法......
目的通过对鱼藤酮导致慢性中毒SD大鼠脑组织标本的病理学检测,探讨鱼藤酮损伤脑神经元的作用机制。方法将20只雄性SD大鼠随机分为......
Determination of Rotenone Residues in Foodstuffs by Solid-Phase Extraction(SPE)and Liquid Chromatogr
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Comparsion of the Effects of Succinate and NADH on Postmortem Metmyoglobin Redcutase Activity and Be
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Parallel relationship between microglial activation and substantia nigra damage in a rotenone-induce
BACKGROUND: Inflammatory injury induced by microglial activation plays an important role in the occurrence and developme......
Rifampicin inhibits apoptosis in rotenone-induced differentiated PC12 cells by ameliorating mitochon
BACKGROUND: Previous studies have shown that rifampicin exhibits neuroprotective effects, but the precise mechanisms rem......
Divalent metal transporter 1 expression and iron deposition in the substantia nigra of a rat model o
Extensive iron deposition has been observed in the midbrain substantia nigra (SN) of Parkinson's disease (PD) patients, ......
Rotenone induces more serious learning and memory impairment than α-synuclein A30P does in Drosophil
Parkinsons disease (PD) is a heterogenous disease caused by multifactorial etiology. PD is characterized by the loss of ......
Previous studies found that iron accumulates in the substantia nigra of Parkinson's disease patients. However, it is sti......
