CCL4-CCR5/CXCL 10-CXCR3介导CD8+T淋巴细胞向食管癌组织的归巢

来源 :中华医学生物免疫学会第二届学术年会 | 被引量 : 0次 | 上传用户：fengyes888

【摘要】

：

目的:食管癌是最常见的消化道恶性肿瘤之一.近年来,过继性免疫细胞治疗在抑制食管癌复发转移中取得了良好的临床疗效.但也有文献报道部分患者对该治疗无应答.动物实验结果显示,效应性T淋巴细胞向肿瘤组织的归巢能力是过继免疫治疗发挥疗效的决定因素之一.趋化因子在淋巴细胞的体内迁移运动中起重要作用,因此研究鉴定T淋巴细胞向食管癌组织归巢中的关键趋化因子对于改进过继性细胞免疫治疗有着重要意义.本研究筛选食管癌患

【作者】

：

王丹刘金燕李峰黄岚陈新峰袁维堂刘金波王贵宪吴长才张毅

【机构】

：

郑州大学第一附属医院生物细胞治疗中心;郑州大学第一附属医院肿瘤科郑州大学第一附属医院生物细胞治疗

【出处】

：

中华医学生物免疫学会第二届学术年会

【发表日期】

：

2014年5期

【关键词】

：

CCL4 CXCL10 CD8 归巢

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Targeting gut microbiome-host genome interactions for cancer and diabetes

The complex metabolic communications between the symbiotic gut microbiota and the host vary extensively between individuals and affect disease risk factors and therapeutic responses among individuals.

会议

Translational Medicine in Obesity-related Cardio-metabolic Syndrome:from Biomarker Discovery to Dise

Diabetes and cardiovascular diseases(CVDs),including coronary heart disease,stroke and other circulatory diseases,are the number one cause of death and disability globally.The increasing incidence of

会议

Quality Standard and Control of Biopharmacueticals in China

In order to assure the safety and efficiency of biopharmacueticals,the CFDA has issued a series of regulations related to biopharmacueticals in China.NIFDC has established a strong platform to perform

会议

BiopharmacueticalsQuality controlSpecificationsRecombinantCytokines

Quantification of HA and NA contents in influenza vaccine

Upon the outbreak of human cases of avian influenza virus(H7N9)infection in China since April 2013,the vaccine development was started soon after manufacturers received the vaccine strains.However,the

会议

influenza H7N9reference reagentsNeuraminidaseUniversal antibody

Genomics of Diabetes and Diabetic complications-translating novel discoveries to personalized medici

Diabetes is a complex disease with heterogeneity in disease phenotype,variable patient response to treatment and possible risk associated with particular therapeutic strategies.The latest guidelines f

会议

Sub-session on “Infections and Vaccines”HIV Vaccine Development as a Translational Medicine Model

It has been challenging to develop an effective HIV vaccine but the lessons learned from HIV vaccine development will have broad impact to the future of translational medicine.The most important lesso

会议

TargetHunter(C)and Diseases-Specific Chemogenomics Knowledgebases for Multiple Myeloma Drug Discover

Chemogenomics is an interdisciplinary research that utilizes chemicals/drugs and associated genomics data to systematically identify and analyze chemicals-protein/protein interactions for the purpose

会议

cloud computingchemogenomics knowledgebasesystem pharmacologymultiple myeloma

Aberrant androgen receptor degradation:implications for prostate cancer therapy

Increasing evidence suggests that aberrant activation of the androgen receptor(AR)plays a pivotal role in prostate cancer development and castration-resistant progression after androgen deprivation th

会议

androgen receptorSPOPp300PTENprostate cancerandrogen deprivation therapy

Lysine Glutarylation Is a New Protein Posttranslational Modification Associated With Glutaric Acidem

We report the identification and characterization of a five-carbon protein posttranslationai modification(PTM)called lysine glntarylation(Kglu).This protein modification was detected by immunoblot and

会议

Application research based on regional medical big data

Firstly,he analyzes situations regarding development of regional medical information platforms at home and abroad,which lays a foundation for the research of big data; secondly,he analyzes challenges

会议

CCL4-CCR5/CXCL 10-CXCR3介导CD8+T淋巴细胞向食管癌组织的归巢

与本文相关的学术论文