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Objective:Research of CD 14 gene promoter 159 polymorphism and allele frequency distribution of Guangdong Han juvenile idiopathic arthritis (JIA) patients,and to explore the relationship between the polymorphism and JIA.Methods:Genotype analysis of 104 cases of JIA cases and 281 healthy children,using the polymerase chain reaction -restriction fragment length polymorphism (PCR-RFLP) method.