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Glucose-responsive micelles for insulin release

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：dfhjaljgjre
【摘 要】
：
In recent years,polymeric micelles self-assembled from amphiphilic polymers have been widely applied in drug delivery fields due to their improved pharmacokinetics and biodistributions [1].Also,polyme
【作 者】
：
Xiuhua Li Wei Wu Jianshu Li 
【机 构】
：
Changzhou Institute of Engineering Technology,Changzhou 213164,China;College of Polymer Science and
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
【发表日期】
：
2014年6期
【关键词】
：
glucose-responsive insulin glucose oxidase block copolymer 
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　　In recent years,polymeric micelles self-assembled from amphiphilic polymers have been widely applied in drug delivery fields due to their improved pharmacokinetics and biodistributions [1].Also,polymeric micelles provide a feasible platform to prevent protein degradation by various enzymes.With further engineered stimuli-responsive functional units,micelles can exhibit intelligent cargo release profile in response to the designed stimulus signal.The smart cargo release behavior could greatly promote the therapeutic efficiency [2] as well as reduce side effects.
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