论文部分内容阅读
Objective:Tocompareand differentiateExtranodalNK/T-celllymphoma,nasaltypefromNasalPolypandInvertedPapilloma withCTimagingfinding. Materials and Methods:Forourcomparativestudy,11patientswithhistologicallyprovenExtranodalNK/Tcelllymphoma,nasal typefrom2010to2016werechosen.AccordingtoAnnArborclassification,7patientswerestagedIand4patientswerestaged Ⅱ.Similarly,134patientswiththediagnosisofNasalpolypand24patientswithInvertedpapillomawereenrolledfrom2010to 2016respectively.Patientwithnoprevioushistoryofheadandneckcancer,previouslyuntreated,histologicaldiagnoseddisease ofnasopharynxandabsentofcoexistingdiseasewereselectedforthestudy.AlltheCTimagesofthepatientswereselectedfrom beforethetreatment.TheCTimageswereevaluatedbytheheadandneckspecialistradiologists. Result:ENKTLwassignificantlydifferentfromNasalpolypandInvertedpapillomaintheinvasionoftumortothesurrounding softtissues.Thedifferencewasobservedintheinfiltrationofnasalvestibule,nasalala,nasalmucosalthicknessand nasopharyngealwall.TherewassignificantdifferencebetweenENKTLandNasalpolypwithnasalvestibuleinvasionbytumor(P =0.003).Similarly,differencewasalsoobservedbetweenENKTLandInvertedpapillomawithnasalvestibuleinvasion(P=0.001). NasalalainvolvementbetweenENKTLandNasalpolypwassignificantlydifferent(P=0.000).Similarly,nasalalainvasionbetween ENKTLandInvertedpapillomawasalsosingnificantlydifferent(P=0.000).Thedifferenceofnasopharyngealwallinfiltrationof ENKTLpatientswithNasalpolypwassignificant(P=0.015).However,therewerenodifferenceobservedbetweenENKTLand NasalPolyp(P=0.092).Furthermore,nasalfloorthickness>2mmornasalseptumthickness>2.5mmbetweenENKTLwith NasalpolypandInvertedpapillomawassignificantlydifference(P=0.000;P=0.000).ENKTLwasalsodifferentwithNasalPolyp intermofpolypoidtumorpattern(P=0.001)however,nodifferencewasobservedwithInvertedPapilloma(P=0.227). Furthermore,therewassignificantdifferencebetweenENKTLwithNasalPolypintheinvolvementoffrontalsinus(P=0.005); however,nodifferencebetweenENKTLandInvertedPapillomawasobservedintheinvolvementoffrontalsinus(P=1.00). Conclusion:ExtranodalNK/Tcelllymphoma,nasaltypetendstoinvadesurroundingsofttissuemoreoftenthanNasalPolyp andInvertedPapilloma.AnypatientwithCTimagingofnasalmasswithsurroundingsofttissueinvasionofnasalvestibule,nasal ala,nasopharyngealwall,nasalfloorthickness>2.0mmornasalseptumthickness>2.5mmshouldpromptclinicianto immediatelyconsiderhistopathologicdiagnosistoruleoutENKTL.