【摘 要】
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Objective To explore the correlation of CT signs with pathological grade and EGFR expression in lung adenocarcinoma. Material and Methods 128 patients including 54 middle or high differentiation and 7
【出 处】
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中华放射学学术大会2016、中华医学会第23次全国放射学学术大会暨中华医学会第24次全国影像技术学术大会
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Objective To explore the correlation of CT signs with pathological grade and EGFR expression in lung adenocarcinoma. Material and Methods 128 patients including 54 middle or high differentiation and 74 low differentiation lung adenocarcinoma were included in the study. The lobulation, spinous sign, spiculation, pleural indentation and vessel convergence of the tumor were analyzed in the pulmonary and mediastinum window under CT scanning. All the patients received detection of EGFR gene mutation. Then analyze the correlation of CT signs with pathological grade and EGFR expression using SPSS software. Results Poorly differentiated tumors were much more than middle or high differentiation ones in >3cm diameter of lung adenocarcinoma(P<0.05). Tumors with deep lobulation, spinous sign and vessel convergence had much higher malignant degree(P<0.05). EGFR mutation in deep lobulation and spinous process group were significantly higher than the other group(P<0.05). Conclusion Lung adenocarcinoma differentiation and EGFR expression had certain relevance with CT signs of the mass. CT has useful clinical value in predicting malignant biological behavior of lung adenocarcinoma.
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