Enhancement of anti-CXCR4 peptide to chemotherapeutic efficiency in acute leukemia cells

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：zhjipi07

【摘要】

：

Most of leukemia cells highly express CXCR4,a seven-transmembrane G-protein-coupled chemokine receptor (GPCR).In bone marrow microenvironment, stromal cells secrete CXCL12, the ligand for CXCR4.

【作者】

：

Hua Guo Xiaojin Li Yanlian Yang Jie Meng Jian Liu Chen Wang Haiyan Xu

【机构】

：

Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences & Peking Union Medical Colle

【出处】

：

International Conference on Nanoscience & Technology,China 2

【发表日期】

：

2013年3期

【关键词】

：

CXCR4 leukemia anti-CXCR4 peptide chemotherapeutic CAM-DR

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　　Most of leukemia cells highly express CXCR4,a seven-transmembrane G-protein-coupled chemokine receptor (GPCR).In bone marrow microenvironment, stromal cells secrete CXCL12, the ligand for CXCR4.

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Enhancement of anti-CXCR4 peptide to chemotherapeutic efficiency in acute leukemia cells

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