Co-culture with human fetal epidermal keratinocytes promotes proliferation and migration of both hum

来源 :第九届全国创伤修复(愈合)与组织再生学术会议暨第二届中欧创面修复学术会议 | 被引量 : 0次 | 上传用户:hhww541
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  Objective: Fetuses and adults follow different repair strategies for the healing of skin wounds.Skin wound healing is primarily controlled by the proliferation and migration of dermal fibroblasts as well as the complex interactions between epidermal keratinocytes (KCs) and dermal fibroblasts.The aim of this study is to investigate the effect of fetal skin epidermal KCs on both human fetal and adult skin fibroblasts.
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Keratinocytes proliferation is critical for the capacity to heal wounds and accumulating evidences have proved that dysregulation of microRNAs is involved in proliferation of keratinocytes.However, th