p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and s

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：njsnw

【摘要】

：

The inhibitory role of p53 in DNA double-strand break (DSB) repair seems contradictory to its tumor suppressing property.The p53 isoform Δ113p53/Δ133p53 is a p53 target gene that antagonizes p53 apopt

【作者】

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Lu Gong Hongjian Gong Xiao Pan Changqing Chang Zhao Ou Shengfan Ye Le Yin Lina Yang Ting Tao Zhenhai Zhang Cong Liu David P.Lane Jinrong Peng Jun Chen

【机构】

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College of Life Sciences, Zhejiang University, Hangzhou, 310058

【出处】

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中国细胞生物学学会2015年全国学术大会

【发表日期】

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2015年4期

【关键词】

：

p53 isoform Δ113p53/Δ133p53 NHEJ HR SSA cell death senescence

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p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and s

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