polyubiquitination相关论文
Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in
TDP43 pathology is seen in a large majority of amyotrophic lateral sclerosis (ALS) cases,suggesting a central pathogenic......
Over-expression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of
The resistance mechanisms that limit the efficacy of retinoid therapy in cancer are poorly understood.Sphingosine kinase......
Key molecular mechanisms controlling T cell receptor (TCR) signaling remain to be fully elucidated.Here we report that N......
Estrogen receptor alpha(ERα)is detected in more than 70%of the cases of breast cancer.Nuclear activity of ERα,a transc......
