dehydroepiandrosterone相关论文
Low DHEAS levels are associated with depressive symptoms in elderly Chinese men: results from a larg
This study investigated the association between depressive symptoms in elderly Chinese men and the total testosterone,de......
Dehydroepiandrosterone suppressing the ovariectomy-induced expansion of CD4+ T cells and TNF-α produ
Postmenopausal osteoporosis (PMO) has been recognized as an inflammatory condition.CD4+ T cell has a key role in the int......
Dehydroepiandrosterone plus climen supplementation prior to in-vitro fertilization cycles may have b
Objective: This study aimed to assess the effect of dehydroepiandrosterone (DHEA) plus climen (estradiol valerate and cy......
Effects of Dehydroepiandrosterone on Embryo Quality and Follicular Fluid Markers in Patients with Di
...
以去氢表雄酮为起始原料,经乙酰化、酯化、Suzuki反应,水解反应,还原反应得到9种去氢表雄酮衍生物(C-1~C-3,D-1~D-3,E-1~E-3),收率......
目的 探讨在肿瘤始发阶段去氢表雄酮（DHEA）的肿瘤化学预防作用及其机理。方法 通过二甲基蒽[7,12-Dimethylbenz(α)-anthracene,DM......
Heyan Kuntai capsule versus dehydroepiandrosterone in treating Chinese patients with infertility cau
ObjectiveTo 在与减少的卵巢的保守(欧洲粪金龟子)引起 .MethodsOne 的不孕对待女人评估 Heyan Kuntai 囊( HYKT )的临床的功效和......
Heyan Kuntai capsule versus dehydroepiandrosterone in treating Chinese patients with infertility cau
OBJECTIVE:To evaluate the clinical efficacy and safety of Heyan Kuntai capsule (HYKT) in treating women with infertility......
目的探索归肾丸对卵巢储备功能低下(DOR)小鼠卵巢Oct-4、MVH及Egr-1的影响。方法将40只C57BL/6J雌性小鼠随机分为正常组、模型组、......
目的探讨脱氢表雄酮(DHEA)对卵巢储备功能下降(DOR)患者在体外受精-胚胎移植(IVF-ET)周期中胚胎质量的影响。方法对接受IVF-ET助孕......
目的设计合成一系列去氢表雄酮衍生物,通过对抑制脂多糖(LPS)诱导小胶质细胞激活作用的筛选,以期发现具有抗神经炎症活性的化合物......
,The Effect of Dehydroepiandrosterone on the Expression of AT1 receptor and TNF-induced ICAM-1 in Va
Objectives To further investigate the molecular mechanism of vasoprotective role of dehydroepiandrosterone (DHEA), we ex......
Aim: This study was conducted to demonstrate the anti-atherosclerotic effect of dehydroepiandrosterone (DHEA) and to inv......
目的 研究脱氢表雄酮(DHEA)对BXSB狼疮性小鼠脾脏淋巴细胞凋亡的影响,并探讨其作用机理.方法 运用流式细胞术、免疫双荧光染色法检......
目的 观察脱氢表雄酮硫酸酯治疗男性骨质疏松症的疗效、安全性。方法 随机单盲对照观察脱氢表雄酮硫酸酯 (DHEAS)服用六个月前后......
Dehydroepiandrosterone indirectly inhibits human osteoclastic resorption via activating osteoblastic
Background Dehydroepiandrosterone (DHEA) is widely known for its beneficial effect on postmenopausal osteoporosis,altho......
Effects of Ning Shen Ling Granule(宁神灵冲剂)and Dehydroepiandrosterone on Cognitive Function in Mice Und
Objective:To investigate the changes of spontaneous and cognitive behavior,and cholinergic M receptors in the brain of m......
Different profiles of mental and physical health and stress hormone response in women victims of int
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
随着不孕症人口高龄化,卵巢储备功能降低的患者逐渐增多,如何改善卵巢储备功能降低患者体外受精-胚胎移植(IVF-ET)的治疗结局一直......
目的 通过观察脱氢表雄酮(DHEA)对胸腺细胞凋亡及CD95/CD95配体(Fag/FagL)表达的影响,探讨在免疫系统中的作用.方法 四甲基偶氮唑......
Effects of Ning Shen Ling Granule(宁神灵冲剂)and Dehydroepiandrosterone on Cognitive Function in Mice Und
Objective:To investigate the changes of spontaneous and cognitive behavior,and cholinergic M receptors in the brain of m......
The plasma level of dehydroepiandrosterone (DHEA) is decreases gradually along with aging. The beneficial effects of DHE......
目的 观察三丁基过氧化氢(tert-butyl hydroperoxide,t-BHP)对血管平滑肌细胞(vascular smooth muscle cell,VSMC)衰老的诱导作用,......
Dehydroepiandrosterone (DHEA), a precursor of androgens and estrogens, has been demonstrated to have effect of preventin......
Dehydroepiandrosterone indirectly inhibits human osteoclastic resorption via activating osteoblastic
Background Dehydroepiandrosterone (DHEA) is widely known for its beneficial effect on postmenopausal osteoporosis,altho......
目的探讨血清皮质醇、硫酸脱氢表雄酮水平(DHEA-S)、急性时相反应蛋白、甲状腺激素与精神分裂症患者精神症状的相关性。方法选取20......
脱氢表雄酮（DHEA）是人体性激素的前体物质，能够在大脑神经元以及星形胶质细胞中从头合成，属于神经甾体。动物实验与临床实验均显示，DHEA......
以去氢表雄酮（1）为原料,经过氯铬酸吡啶（PCC）氧化得到雄甾-4-烯-3,6,17-三酮（2）,然后在Co2＋存在下用NaBH4还原,得到芳香酶的强效抑制剂3β......
目的 探讨脱氢表雄酮（dehydroepiandrosterone,DHEA）对高脂诱导的血管细胞黏附分子-1（VCAM-1）表达的影响,以及全反式维甲酸在这一过程......
昆明种雄性小鼠32只，随机分为4组。脱氢表雄酮（DHEA）日摄取量分别为0（对照组）、20、40和60mg／kg，试验期52d。各组分别在42日龄、72日龄处......
目的观察脱氢表雄酮对氧化型低密度脂蛋白诱导的血管平滑肌细胞分泌单核细胞趋化蛋白1的影响,并探讨其作用机制是否与细胞色素P450......
流行病学调查证实，动脉粥样硬化（Atherosclerosis，AS）的危险因素有脂质代谢异常、高血压、糖尿病、吸烟、性别等。男性人群的发病率较......
目的：分析脱氢表雄酮（DHEA）对CD40L刺激的人脐静脉内皮细胞（HUVECs）的一氧化氮（NO）、内皮素-1（ET-1）水平及ET-1mRNA和内皮源性NO合酶（eNOS）mRN......
目的通过比较脱氢表雄酮(DHEA)联合高脂饮食及单纯DHEA构建多囊卵巢综合征(PCOS)的大鼠模型,探究更理想的多囊卵巢大鼠的建模方法......
目的:研究脱氢表雄酮(DHEA)对大鼠实验性骨关节炎(OA)的影响.方法:40只大鼠随机分4组:正常对照组、模型对照组、DHEA大、小剂量组.......
目的:观察脱氢表雄酮(DHEA)对哮喘大鼠血嗜酸粒细胞(EOS)数量及IL-4、IFN-γ的水平影响。方法:30只大鼠建立哮喘模型后随机等分为......
目的：分析不同产地的山药中脱氢表雄酮的含量,为山药质量标准的建立提供参考。方法：采用高效液相色谱分析,Sun-Fire C18色谱柱（4.6mm&......
目的研究脱氢表雄酮（DHEA）对成骨细胞雌激素受体（ER）亚型的调节及防治绝经后骨质疏松的作用机制。方法取新生2—4dBALB／c小鼠颅骨，用酶消......
目的 探讨脱氢表雄酮（DHEA）对鼠成骨细胞（OB）芳香化酶和雌激素受体（ER）亚型转录的调控作用。方法 颅骨酶解法原代培养OB，体外模拟雌激素撤......
目的通过生物转化对去氢表雄酮进行结构修饰,以期获得更有意义的转化产物.方法利用唐古特山莨菪毛状根液体悬浮培养体系对去氢表雄......
目的：研究脱氢表雄酮（dehydroepiandrosterone，DHEA）对血管性痴呆小鼠学习和记忆能力的改善作用及可能机制。方法：将小鼠随机分为假手术......
了解放射免疫法测定血清脱氢表雄酮（dehydroepiandrostemne，DHEA）的可靠性、抑郁症患者DHEA水平及抗抑郁治疗后的变化。选取抑郁症患......
目的 观察脱氢表雄酮（DHEA）对去势雌兔免疫功能的影响.方法 24只3月龄新西兰雌兔随机分为正常对照组、假手术组、去势对照组（卵巢切除......
目的:观察脱氢表雄酮(DHEA)对体外培养的Burkit淋巴瘤(Raji)细胞抗氧化能力的影响.方法:用一定浓度的DHEA作用于体外培养的Raji细......
目的脱氢表雄酮（dehydroepiandrosterone，DHEA）是成人体内最为丰富的来源于肾上腺的甾体激素，文中探讨DHEA对氧化型低密度脂蛋白（oxidiz......
目的观察大鼠动脉超氧化物歧化酶（SOD）活性和丙二醛（MDA）含量的增龄性变化及脱氢表雄酮（DHEA）的干预作用。方法实验分三组：18月龄鼠组；DHEA......
目的探讨银屑病患者血清去氢表雄酮（DHEA）和硫酸去氢表雄酮（DHEA-S）水平的临床意义。方法检测银屑病患者（观察组）和健康人群（健康对照组）血......
目的:建立去氢表雄酮片剂的高效液相色谱(HPLC)测定方法.方法:采用μ-BondapakC18柱,以CH3OH∶H2O(75∶25)为流动相,检测波长为292......
MIF May Participate in Pathogenesis of Polycystic Ovary Syndrome in Rats through MAPK Signalling pat
The polycystic ovary syndrome (PCOS) model was established in fats and correlation between the expression of macrophage ......
目的用脱氢表雄酮（DHEA）制造大鼠的多囊卵巢综合征（PCOS）模型，探讨类固醇激素合成急性调节蛋白（STAR）在多囊卵泡中的表达，及其和卵巢激素分......
