cynomolgus相关论文
Aging is closely related to physiology and disease development in animals.Gut microbiota varies with lifecycle and exert......
Evaluation of human monoclonal antibody toxicity, toxicokinetics and immunogenicity in cynomolgus mo
Aim: A human monoclonal antibody was administered intravenously for 4-week in cynomolgus monkeys.The aim of this study w......
A validation safety pharmacology study of the central nervous system, employing a functional observa
Aim: The objective of this study was to establish and validate a functional observational battery (FOB) at the Center fo......
Gene Expression Profile of Cynomolgus Peripheral Blood monocyte with Type 2 Diabetes Mellitus in its
Background Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disease and妙far the most common；the overall pre......
Mutations of PTEN-induced kinase Ⅰ(PINK1)cause early-onset Parkinson's disease(PD)with selective neurodegeneration in ......
目的：研究猪来源抗胸腺细胞球蛋白（ATG）对食蟹猴免疫功能的影响。方法 ATG倍比稀释与食蟹猴淋巴细胞孵育，流式检测细胞毒；ATG单纯给药组......
在某一种族和社会中,绝经前妇女较其配偶具有预防冠状动脉粥样硬化能力,是因血浆脂蛋白胆固醇浓度,特别是高密度脂蛋白胆固醇(HDL......
亚硝基甲基脲(NMU)是一种N-亚硝基化合物,食物中有微量存在,曾报导也可能在人体胃中通过内源性形成。在实验条件下,N-亚硝基化合......
为构建食蟹猴T2DM进程序列模型，将36只食蟹猴分为4组，分别采用标准基础膳食和高能量膳食（高糖膳食、高脂膳食和高糖高脂膳食）进行诱导，......
目的 观察H5N1型禽流感病毒对中国非人灵长类动物的易感性并建立动物模型.方法 将病毒通过滴鼻接种实验猴,观察感染后动物的临床症......
目的：2型糖尿病（type2diabetesmellitus，T2DM）及其并发症的迅速蔓延已经成为严重威胁人类健康的世界性难题。食蟹猴T2DM模型可以模拟人......
Comparison of gene expression in cynomolgus monkeys with preclinical type II diabetes induced by dif
Background:C ynomolgus disease models that are similar to the preclinical stage of human type 2 diabetes mellitus(T2 DM)......
历年的数据表明,剖检病变出现频率最高的组织器官是肺脏32.05%、其次是肠道16.29%、胃部4.4%、肠道寄生虫2.19%,预示腹泻（痢疾）、肺......
目的 观察不同年龄段雌性食蟹猴血清铁蛋白与雌激素及其骨转换指标,探讨铁蛋白与雌激素及骨转换指标变化的相关性。方法 选用雌性......
目的 调查食蟹猴群体的HbA1c水平并建立其背景数据库。方法 采集后肢静脉血以高效液相色谱法测定176只（雌性88只；雄性88只）食蟹猴的Hb......
Plasma lipoprotein(a) (Lp(a)) is known to be a strong independent risk factor for ischemic heart disease. However, it is......
