cyclosporine相关论文
One case report of intervention in immunosuppressive agents convertion from cyclosporine to tacrolim
Aim: To explore the work pattern of clinical pharmaceutical care associated with immunosuppressive agents convertion fro......
Relationship between genetic polymorphisms of PXR and Cyclosporine blood concentration of stable hea
Objective To investigate the correlation between cyclosporine blood concentration of heart transplant patients and PXR g......
Association of CYP3A4*18B and CYP3A5*3 polymorphisms with the pharmacokinetics of cyclosporine in Ch
Background—Cyclosporine is a substrate of cytochrome P450 3A (CYP3A),some of the single nucleotide polymorphisms (SNPs)......
OBJECTIVE The present study was aimed to evaluate whether the interindividual variation of cyclosporine dosages and bloo......
The effect of CYP3A5 polymorphism on dose-adjusted cyclosporine concentration in renal transplant re
Cyclosporine (CsA) is a substrate of cytochrome P450 (CYP) 3A5 and has a narrow therapeutic range with large inter-indiv......
Effect of MDR1 C1236T Polymorphism on Cyclosporine Pharmacokinetics: a systematic review and meta-an
Objective: Cyclosporine is one of the immunosuppressive drugs,whose pharmacokinetic characteristics vary greatly among i......
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Cyclosporine treatment in idiopathic membranous nephropathy nephrotic syndrome in adults: a retrospe
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Lymphoproliferative disorders in inflammatory bowel disease patients on immunosuppression: Lessons f
Immunosuppressive agents, such as thiopurines, methotrexate, and biologics, have revolutionized the treatment of inflamm......
Azathioprine is essential following cyclosporine for patients with steroid-refractory ulcerative col
AIM: To evaluate long-term prognosis following cyclosporine treatment by examining the rate of surgery avoidance among c......
近年来,许多学者就环孢素A(cyclosporine A,简称CsA)的肾毒性,进行了日趋深入的研究,但目前各家报道不一,许多问题还存在争议。实......
环孢素 A 与肾移植的概况肾移植作为一种临床治疗手段经历了30余年的历史,在各个方面都有很大进展,特别60年代硫唑嘌吟(azathlopr......
本文研究环孢菌素 A(cyclosporine A,CYA)对类风湿性关节炎(rheumatoid arthritis,RA)患者肾功能的作用,并监测 CYA 和非类固醇抗......
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EfectsofcyclosporineAonserumandurinarysolubleinterleukin┐2receptorinpatientswithlupusnephritisTangZhen......
Experimental study on cyclosporine A drug delivery system in prevention of posterior capsule opacifi
Objective To study the effect of cyclosporine A drug delivery system (CsA-DDS) on the prevention of posterior capsule op......
Aplastic anemia associated with dyskeratosis congenita treated with antilymphocyte globulin and cycl
Dyskeratosis congenita (DC) is a severe inherited disease characterized by a triad of clinical manifestations including ......
MANY cases of pure red cell aplasia(PRCA)were mediated by over-function of immune cells,and responded well to immunosupp......
Effect of cyclosporine-A on electrophysiological properties of atria in tachycardia-induced atrial f
Objective To investigate the effects ofciyclosporine-A (CsA),a calcineurin (CAN) inhibitor,on electrophysiological prope......
Disease control by regulation of P-glycoprotein on lymphocytes in patients with rheumatoid arthritis
The main purpose of treatment of rheumatoid arthritis(RA) with disease modifying antirheumatic drugs(DMARDs) is to contr......
Ischemia/reperfusion injury and cardioprotective mechanisms:Role of mitochondria and reactive oxygen
Reperfusion therapy must be applied as soon as possible to attenuate the ischemic insult of acute myocardial infarction(......
Objective:To evaluate the efficacy and safety of Pai-Neng-Da Capsule(派能达胶囊t panaxadiol saponins component,PND),a ne......
Treatment of transfusion-dependent nonsevere aplastic anemia with cyclosporine A plus ATG/ALG versus
Objective To determine whether cyclosporine A(CsA)plus andronges was as effective as the current standard immunosuppress......
Objective: To study the synergistic effect of ICOS-Ig combined with cyclosporine (CsA) on mouse heart transplantation an......
目的探讨重型再生障碍性贫血(SAA)患儿进行抗胸腺细胞球蛋白(ATG)联合环孢素(CSA)免疫抑制治疗的疗效。方法收集SAA患儿20例，均给予......
目的 建立超高效液相色谱-质谱法测定小鼠角膜中环孢素的含量.方法 流动相:甲醇-水(90∶10),色谱柱:Hypersill C18柱(100 mm×2.1 ......
目的:研究肾移植术后患者多药耐药相关蛋白(MRP2/ABCC2)基因多态性对环孢素(CsA)肝功能异常的影响.方法:入选的339例肾移植受者均......
Effects of mycophenolate mofetil vs cyclosporine administration on graft survival and function after
AIM: To develop an experimental model of islet allotran-splantation in diabetic rats and to determine the positive or ad......
1例66岁女性因高脂血症服用脂必妥（0.35 g，3次/d）。服药4 d后出现三角肌酸痛、无力；服药25 d时出现全身酸痛、乏力、上下楼梯困难；服药4......
Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation: Effects o
AIM: To determine the effects of the calcineurin inhibitors, cyclosporine and tacrolimus, on hepatitis C virus (HCV) rep......
目的了解克拉霉素对血液病患者环孢素血药浓度的影响。方法收集2012年2月1日至2016年1月31日在北京医院接受环孢素治疗血药浓度不......
1例35岁男性患者因移植物抗宿主病致肝硬化、门脉高压症而给予甲泼尼龙(40 mg、2次/d)和吗替麦考酚酯(750 mg、2次/d)口服。用药前......
1例有白塞病病史的41岁男性急性髓系白血病患者异基因造血干细胞移植期间静脉泵入他克莫司(2.5～3.0 mg/24 h)，维持血药浓度在10.0～15.......
1例60岁女性结缔组织病患者服用环孢素(300 mg、1次/d)第2天出现咽部疼痛，第3天出现便血、腹胀、腹痛，第14天出现双目失明、短暂性双......
Therapy of central pontine myelinolysis following living donor liver transplantation: Report of thre
We analyzed the clinical manifestations and experiences of diagnosing and treating central pontine myelinolysis followin......
目的 观察γ干扰素(IFN-γ)和肿瘤坏死因子α(TNF-α)诱导的骨髓问充质干细胞(MSC)的免疫抑制作用及环孢素A(CsA)对其的影响.方法 ......
目的 探讨环孢素对N-丁基-N-(4-羟丁基)亚硝胺(BBN)诱导的大鼠膀胱肿瘤细胞增殖、凋亡及肿瘤新生血管形成的影响.方法实验组大鼠10......
Objective: To investigate the response of the xenograft endothelium in the concordant hamster to rat cardiac xenotranspl......
扁平苔藓(LP)为一侵犯皮肤和粘膜的慢性疾病,病因不明。目前治疗糜烂型OLP的方式包括从加强控制OLP斑块的措施到局部或全身应用皮......
环孢霉素(cyclosporine)对许多口腔粘膜病有效,但全身应用因剂量大而有许多副作用。局部应用虽减少了副作用的发生。但药物渗透性......
Acute respiratory distress syndrome after liver transplantation: etiology, prevention and management
Objective: To study the etiology, prevention andmanagement of acute respiratory distress syndrome(ARDS) after liver tra......
INTRODUCTIONThe T-cell dependent specific liver injury in mice induced byconcanavalin A (ConA) is a newly established e......
Ulcerative colitis (UC) is an inflammatory destructive diseaseof the large intestine occurred usually in the rectum and......
Objective To investigate the impact of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection on the long-term su......
Cytomegalovirus infection in severe ulcerative colitis patients undergoing continuous intravenous cy
AIM: To investigate active cytomegalovirus (CMV) infection following the cyclosporine A (CyA) treatment of steroid-refra......
Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation:Effects on
AIM:To determine the effects of the calcineurininhibitors,cyclosporine and tacrolimus,on hepatitis Cvirus(HCV)replicati......
Time, times and timing are key words in inflammatory bowel diseases (IBD). The leifmotif of this issue o World Journal o......
Although systemic steroids are highly efficacious in ulcerative colitis (UC), failure to respond to steroids still poses......
