chloroquine相关论文
目的 肺癌的发病率和致死率高居世界恶性肿瘤首位.尽管肺癌的诊断与治疗治疗已取得进展,但其发病率和致死率仍呈逐年上升的趋势,因......
Autophagy inhibitors increase the susceptibility of KRAS-mutant human colorectal cancer cells to a c
RAS-driven colorectal cancer relies on glucose metabolism to support uncontrolled growth.However,monotherapy with glycol......
Reviving chloroquine for anti-SARS-CoV-2 treatment with cucurbit[7]uril-based supramolecular formula
The wide-spreading SARS-CoV-2 virus has put the world into boiling water for more than a year,however pharmacological th......
[objectives]This is the first study to investigate the hepatoprotective effect of CQ on acute liver injury caused by car......
NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 by suppression of autophagosome
Objective:Combretastatin A-4 (CA-4),a tubulin depolymerising agent,shows promising anti-tumor efficacy and has been unde......
...
目的 Malignant pleural effusion(MPE)is associated with a poor prognosis in lung cancer.Currently,no effective cure exist......
PO367-The impact of chloroquine treatment on the pattern reversal visual evoked potentioals in patie
...
Purpose:Autophagy is the major regulated mechanism for degrading long lived proteins and the only known pathway for degr......
The Synergistic Antitumor Effect of Co-delivery of Salinomycin and Chloroquine Via Nano-liposomes Ag
Hepatocellular carcinoma is the most frequently diagnosed cancer in the world.Liver cancer stem cells (LCSCs) are consid......
Development and validation of an HILIC-MS/MS method by one-step precipitation for chloroquine in min
Background: Quantification of polar compounds such as chloroquine by revered-phase liquid chromatography is a challenge ......
Low Concentrations of Chloroquine and 3-Methyladenine Suppress the Viability of Retinoblastoma Cells
Background: To study the inhibition of retinoblastoma cell viability by two commonly usedautophagy inhibitors, chloroqui......
The islet of Langerhans is the most important organ for glucose homeostasis.It is majorly composed of alpha cells secret......
Since chloroquine(CQ)and hydroxychloroquine(HCQ)can inhibit the invasion and proliferation of severe acute respiratory s......
Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamo
Sulforaphane(SFN), a natural anti-tumor compound from cruciferous vegetables, has been reported to induce protective aut......
1.It is reported that bitter tastants decrease blood pressure and relax precontracted vascular smooth muscle.However......
Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles through restoring aut
Aim: To study the role ofautophagy in muscle establishment with long term regular exercise.Methods: The female mouse......
A graphical index is a numeric value corresponding to a graph which is structurally invariant and in molecular graph the......
作者报告8例黄疸型病毒性肝炎,經其他葯物治疗无效,改用磷酸氯喹啉收到满意效果。男性5例,女性3例,年龄自22—79岁。氯喹啉用法是......
氯喹作为传统的老药，不仅用于抗疟疾治疗，还用于类风湿关节炎、红斑狼疮等疾病的治疗。近年发现氯喹还具有抗肿瘤作用，并在克服肿瘤耐......
Objective:To compare the applicability of the SYBK Grcen-Ⅰ assay with the standard schizont maturalion assay,for determ......
...
...
Ａ５４－ＫＤａＰｒｏｔｅｉｎＯｖｅｒｅｘｐｒｅｓｓｅｄｂｙＣｈｌｏｒｏｑｕｉｎｅ－ｒｅｓｉｓｔａｎｔＰｌａｓｍｏｄｉｕｍＢｅｒｇｈｅｉＡＮＫＡＳｔｒａｉｎＬｉｃａｏｄｅ（李高德），ｅｔａｌ．中国药理学报，１９９３；１４（１）：９Ｕｓｉｎｇａｎｉｎｓｏ...
A54-KDaProteinOverexpressedbyChloroquine-resistantPlasmodiumBergheiANKAStrainLicaode, et al. Chin......
Pharmacological and cardiovascular perspectives on the treatment of COVID-19 with chloroquine deriva
The novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19) and an......
目的监测云南省盈江县中缅边境恶性疟原虫对氯喹、哌喹的体外敏感性,了解两种抗疟药有无交叉耐药。方法选取2007~2009年当地病人体......
AIM: To study the effect of chloroquine on the expression of human clotting factor IX (hFIX) in mice. METHODS:Hydrodynam......
,Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restorin
...
...
Eukaryotic elongation factor-2 kinase (eEF-2K),a negative regulator of protein synthesis,has been shown to play an impor......
Preliminary evidence from a multicenter prospective observational study of the safety and efficacy o
Effective therapies are urgently needed for the SARS-CoV-2 pandemic.Chloroquine has been proved to have antiviral effect......
46 inbred NIH mice were infected by chloroquine resistant strain of Plasmodium yoelii. The ultrastructure changes were o......
Role of adjunctive treatment strategies in COVID-19 and a review of international and national clini
The coronavirus disease (COVID-19) pandemic has led to a global struggle to cope with the sheer numbers of infected pers......
自2019年12月,武汉暴发了一种新型冠状病毒(COVID-19)感染,迅速蔓延至我国各省市及全球26个国家,防疫形势十分严峻.但是目前尚无特......
目的研究氯喹(chloroquine,CQ)对杨梅素诱导的He La细胞凋亡的影响。方法体外培养宫颈癌He La细胞,实验分为Control组、单加杨梅素......
Objective: To investigate the reversal effect of CQ11, a chloroquine derivative, on multidrug resistance (MDR) in doxoru......
目的探讨氯喹(CQ)对小鼠移植性肉瘤S_(180)的抑瘤作用及其可能机制。方法采用40只S_(180)荷瘤小鼠分为模型组,氯喹低剂量组,氯喹中......
A graphical index is a numeric value corresponding to a graph which is structurally invariant and in molecular graph the......
Objective: To investigate the reversal effect of CQ11, a chloroquine derivative, on multidrug resistance (MDR) in doxoru......
目的 了解我国氯喹加伯氨喹八日疗法对中缅边境地区间日疟患者的治疗效果.方法 便于追踪、满足纳入条件的单纯间日疟患者且同意参......
目的 观察氯喹联合中药治疗口腔糜烂型扁平苔藓的短期疗效.方法 选择糜烂型扁平苔藓患者40例,按数字表法随机分成两组(对照组和治......
Although the anti-malaria drug chloroquine (CQ) has been shown to enhance chemotherapy and radiation sensitivity in clin......
目的 观察氯喹对戊四氮致痫大鼠皮质和海马区腺苷激酶(ADK)表达的影响,探讨ADK与癫痫发作的关系及氯喹在癫痫发生过程中的作用. 方......
目的观察丹参和金因肽联合治疗口腔糜烂型扁平苔藓(OLP)的短期疗效.方法将78例患者随机分为两组,治疗组40例采用丹参和金因肽联合......
目的:观察复方萘酚喹与氯喹治疗间日疟的临床疗效.方法:以显微镜血检单纯间日疟原虫阳性患者为观察对象,药物为复方萘酚喹(萘酚喹4......
目的探讨氯喹对内毒素血症小鼠的保护作用以及抑制内毒素引起的细胞因子释放情况.方法清洁级昆明小鼠40只,随机分为LPS、氯喹、氯......
本研究观察了磷脂酶A_2(PLA_2)对培养的小牛肺动脉内皮细胞的损伤作用和氯喹的保护作用。结果发现:PLA_2可使膜通透性升高,硝酸镧......
目的:探究氯喹对CoCl2诱导的视网膜神经节细胞凋亡的保护作用。方法:小鼠视网膜神经节细胞RGC-5细胞加入300μmol/L CoCl2及30μmo......
[目的]明确水稻田稗草对二氯喹啉酸的耐药性机制。[方法]采用盆栽试验,测定二氯喹啉酸对耐性生物型稗草体内超氧化物歧化酶(SOD)、......
