在获得n Bone杂志的授权后，本文对该刊发表于2019年2月的文章[Wu J, Wang A, Wang X, et al. Rapamycin improves bone mass in......

Development of thoracolumbar vertebra (TLV) and rib primordium (RP) is a common evolutionary feature across vertebrates,......

Vascularization is an important early indicator of osteogenesis involving biomaterials.Bone repair and new bone formatio......

In order to reduce implant-related infections and improve early osseointegration,we performed HF+anodic oxidation on the......

Objective: To investigate the osteoblastogenic activity of the ethyl acetate (EtOAc) extract of Smilax glabra Roxb roots......

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The study conveys an idea to enhance the osseointegration of titanium implant (Ti) through modulating macrophages M2 pol......

A biomimetic scaffold based on mineralized recombinant collagen,nano-hydroxyapatite/recombinant human-like collagen/poly......

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The multifunctional composite scaffolds with both excellent angiogenic and osteogenic activities are highly desirable to......

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Although titanium(Ti)based medical devices have been used clinically for more than 30 years,there are still weaknesses f......

The microenvironment has been shown to regulate cellular functions including cell growth, differentiation, proliferation......

Losing differentiation potential is a serious problem which frequently emerges during subculturing adult stem cells in v......

Bone callus generates along with fracture healing,which is commonly discarded during surgical procedures.The aim of this......

Here,we developed a novel optimization algorithm and determined the effects of different properties of implanted biomate......

INTRODUCTION Periosteal cells are a heterogeneous population that has a potential of osteogenic differentiation.Seeding ......

Engineering scaffolds combinging natural bio-mineral and artificially synthesized material hold promising potential for ......

In this study,novel bioactive calcium sulfate/oyster shell(CS/OS)composites were prepared.Comparing to CS scaffold,the C......

Purpose: Osteoporosis is associated with the disordered balance between osteogenesis and adipogenesis of bone marrowderi......

This study was to investigate the efficacy of P-glycoprotein(P-gp)overexpression on bone marrow mesenchymal cell(BMSC)os......

Objective:Recently,accumulatingevidenceshaveshownthatexosomes,akeycomponentofcellparacrine secretion,canexerttherapeutic......

miR-9-5p and low-density lipoprotein receptor-related protein 5 (LRP5) play vital roles in multiple biological processes......

Because patient bone defects are usually varied and complicated in geometry,it would be preferred to fabricate custom-ma......

Bone scaffolds are crucial for meeting the treatment need of segmental bone defects caused by trauma,tumor excision or c......

Background:Despite their benefits,tissue engineering bones (TEB) were constrained by certain issues with respect to clin......

Objective Connexin(Cx)43 and microRNA(miR)-206 play an important role in osteogenesis. However, their role in steroid in......

Background: S100B is expressed and released by adipocytes,and is positively correlated with body mass index,but the dire......

Peripheral blood mesenchymal stem cells(PBMSCs)may be easily harvested from patient,therefore permitting autologous graf......

Introduction: Adipose derived stem cells(ADSCs)have recently attracted focus in regenerative medicine because they are e......

OBJECTIVEBonetissueengineeringhasattractedmuchattentionasanewtherapicapproachofbonedefects. Thisstudywascarriedouttoveri......

Objective:Titanium has been widely used in the orthopedic and dental fields,however,the inert nature of Ti makes it unsu......

Osteosarcoma(OS)is the most common primary malignancy of bone and is usually associated with poor prognosis due to its h......

Excessive reactive oxygen species (ROS) play an important role in the development of osteoporosis. Ophiopogonin D (OP-D)......

Aims: Reactive oxygen species (ROS) is a significant pathogenic factor of osteoporosis. Ginsenoside-Rb2 (Rb2), a 20(S)-p......

Sterilizationforhumanallograftsisimportantbecauseofthewidespreaduseoftransplantsinprosthesis revision,spinaldefectsandre......

Study Design:An animal experiment using rat posterolateral spinal fusion model. Objective:To observe the spatiotemporal ......

Grapheneisapromisingnanomaterialasapharmacologicalvehicleinmedicalmaterialfieldsduetoitsuniqueproperties.......

Grapheneisapromisingnanomaterialasapharmacologicalvehicleinmedicalmaterialfieldsduetoitsuniqueproperties.......

Background and aims: RIA reamings harvested from Reamer/Irrigator/Aspirator system provides quantity mesenchymal stem ce......

Hypoxia-inducible factor 1α (HIF1α) is expressed in all metazoan organisms that play crucial roles in angiogenesis, er......

Objective Osteoporosis has become one of the most common skeletal disorders for the elderly, postmenopausal women and th......

The influence of Mg-1Ca-xwt.%Sr (x=0.2, 0.5, 1.0, 2.0) alloys on the osteogenic differentiation and mineralization of pr......

Extracorporeal shockwaves (ESWs) have been widely used in the clinic for delayed bone fracture union and nonunion....

Objective: The objective of this study is the effect of cerebrospinal fluid pulsation (CSFP) on the osteogenesis and rem......

3D printed titanium scaffolds provide a valuable alternate for bone graft, but the low bioactivity restricts its extensi......

In this study, we determined the effect of cerebrospinal fluid pulsation (CSFP) on the osteogenesis and remodeling of de......

Heat shock proteins have protective effects when cells are exposed to stress. However, the relationship between extracel......

In order to improve the osteogenic performance of titanium implants contaminated by the residual bacterial debris and li......

Objective:ToobserveboneregenerationofVancomycin-loadedBHA/PAAscaffoldbothinvitroandinvivo. Methods:Invitrotests,MG63cell......