Neurotoxicity相关论文
Ghrelin is a neuropeptide that has various physiological functions and has been demonstrated to be neuroprotective in a ......
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Exposure to DE-71 alters thyroid hormone and gene transcription in the hypothalamic-pituitary-thyroi
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In the framework of the Italian Biomonitoring Programme(PROBE),a cohort of about 500 adolescents aged 13-15 years living......
Objective: This study was designed to approach the hypothesis that oxidative stress mediates chromium-induced cytotoxici......
Objective: This study is to explore the genetic toxicity of cobalt nanoparticles on retinal cells and brain cells in rat......
Long-term brain tissue monitoring after hemibrain irradiation in rats using proton magnetic resonanc
Background: Radiation-induced brain injury is one of the most serious complications of radiation therapy(RT).It can lead......
Purpose: To evaluate metabolic changes in the brain after half-brain irradiation in mice with different irradiation doze......
Decreased 5-methylated cytosine(5-mC)content of genome was induced in dopaminergic neurons in the su
Parkinsons disease(PD)is a progressive neurodegenerative disease related to aging,and is due to the degeneration and dea......
Switching of N-methyl-D-aspartate (NMDA) receptor-favorite intracellular signal pathways from ERK1/2
Excitotoxicity mediated by overactivation of N-methyl-D-aspartate receptors (NMDARs) has been implicated in a variety of......
Introduction:Transient receptor potential vanilloid 4 (TRPV4) is widely expressed in the central nervous system and can ......
Hydrogen sulfide antagonizes Formaldehyde-induced neurotoxicity by inhibition of autophagy via upreg
Formaldehyde (FA) has neurotoxicity and we have previously demonstrated that hydrogen sulfide (H2S),the third gasotransm......
Global and Targeted Metabolomics Reveal That Bupleurotoxin Induces Cerebral Lesion bv Inhibiting GAB
Polyacetylenes are widely present in food and herbs, while these compounds have specific neurotoxicitv, and even cause d......
Air pollution increasingly becoming a severe public health problem attracts extensive concerns in masses.Traffic-related......
Isoflurane Inhibits Embryonic Stem Cell and Induces Pluripotent Stem Cell Self-renewal by Down-regul
Many pregnant women are exposed to inhalation anesthetics (including isoflurane) for non-obstetric surgery1.The commonly......
Neurotoxicity is one of the major potential side effects of colistintherapy.However,the mechanistic aspects of colistin-......
CdTe quantum dots induce neurotoxicity modulated by the neurotransmissions of glutamate, serotonin a
Quantum dots (QDs), considered as altematives of conventional fluorescent dyes, are an increasingly used class of nanopa......
Involvement of decreased neuroglobin protein level in cognitive dysfunction induced by l-bromopropan
1-Bromopropane (1-BP) is used as a substitute for ozone-depleting solvents (ODS) in industrial applications.1-BP could d......
BDNF-TrkB pathway mediates the protection of hydrogen sulfide against formaldehyde-induced neurotoxi
[Backgroud and Objective] Formaldehyde (FA) can induce neurotoxicity.We have previously found that Hydrogen sulfide (H2S......
With the rapid development of nanotechnology, nanomaterials are widely used and developed in modem industry and life.Sil......
Craving:the Neurotoxic and Social-cognitive Effects of Drugs Consumptions of Adults, Adolescences, i
Substances of abuse affect cognition in a number of ways.One of its indirect effects include craving, which has been an ......
Noble dendrobium polysaccharides protects neuron against LPS-induced neurotoxicity in primary rat ne
OBJECTIVE To investigate the protective effect of Noble dendrobium polysaccharides (NDP) on inflammatory fac tors, which......
Tetrachlorobenzoquinone exerts neurological pro-inflammatory activity by promoting HMGB1-TLR4 signal
Pentachlorophenol(PCP)has been extensively used as herbicide and insecticide in the agriculture and industry due to its ......
Di-(2-ethylhexyl)phthalate(DEHP)is one of the most widely used phthalates....
Pesticides are a class of biocides used to incapacitate,kill or mitigate any pest,especially in the agriculture practice......
Investigation of the protective effect of total glucosides from paeony on strychnos alkaloids-induce
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卡西酮类策划药的结构和药效与苯丙胺类兴奋剂相似，多通过对已管制毒品进行细微化学修饰或全新设计、筛选获得，使人体产生类似或更强......
Dopaminergic neurotoxicity is characterized by damage and death of dopaminergic neurons.Parkinson\s disease(PD)is a neu......
全身麻醉药对发育期大脑具有潜在神经毒性作用。组蛋白去乙酰化酶抑制剂（histone deacetylase inhibitors, HDACIs）可通过提高细胞内......
This paper analysis chemotherapy-induced peripheral neuropathy(CIPN)caused by related chemotherapeutic drugs and propose......
Lead(Pb)neurotoxicity has received renewed interest with the growing evidence that Pb contributes to Alzheimers dise......
Propofol is currently one of the most widely used intravenous anesthetics and has been indicated to induce cognitive......
Alzheimers disease (AD) is the most common type of senile dementia,which often develops in elderly or presenile indi......
Chronic exposure to low-levels of organophosphate (OP) compounds, such as chlorpyrifos (CPF), induces oxidative stre......
目的分析华中科技大学同济医学院附属协和医院含奥沙利铂化疗方案不良反应的规律及特点,为临床合理应用提供参考。方法搜集2016年5......
目的探讨miR-133b在甲基苯丙胺(methamphetamine，MA)依赖大鼠脑内表达情况及其对神经元毒性损伤的调控作用。方法通过腹腔内连续注......
Effects of natural-cerebrolysin-containing serum on neurotoxicity and synaptogenesis in amyloid-beta
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Lead acetate in drinking water is toxic to hippocampal tissue Measuring relative protein changes usi
BACKGROUND:Lead can cause structural changes in the hippocampus, followed by damage to leing and memory functions, but i......
Neuroprotective potential ofIndigofera oblongifolia leaf methanolic extract against lead acetate-ind
Lead (Pb) is one of the most common environmental toxicants, exposure to which can cause signiifcant neurotoxicity and a......
机体在环境中的过量氟暴露可导致多种健康危害，其中神经系统损害尤为严重。已经有大量实验及临床资料证实，摄入环境中过量的氟会引起......
目的探讨在异氟烷麻醉总时间一致的前提下，不同麻醉时间间隔对发育期大鼠急性脑损伤后认知行为的影响。方法选用生后7 d的SD大鼠，按......
全身麻醉是通过全身麻醉药作用于中枢神经系统（CNS），尽管最初人们认为全身麻醉药对CNS的影响是可逆的，并不会对大脑造成长期不良影响，但......
Protective effect of ashwagandha (Withania somnifera) against neurotoxicity induced by aluminum chlo
Objective:To evaluate the neuroprotective effect of ashwagandla extract against aluminum chloride-induced neurotoxicity ......
Polygonum minus ethanolic extracts attenuate cisplatin-induced oxidative stress in the cerebral cort
Objective: To explore the protective effect of Polygonum minus ethanolic extract on cisplatin-induced neurotoxicity. Met......
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乙醇暴露能够导致神经元变性及神经元死亡，引起严重的神经系统损伤。发育期的神经系统对乙醇更为敏感，产前摄入乙醇可导致胎儿酒精谱......
目的 探讨2,3,7,8-四氯二苯并二(噁)英(TCDD)的神经毒性.方法 选择人星形胶质细胞和人神经母细胞瘤细胞(SH-SY5Y),4个染毒组和对照......
氨甲喋呤(MTX),其结构与叶酸及二氢叶酸还原酶抑制剂类似。常用于治疗风湿、肿瘤、炎症和皮肤疾病等。近年来,甲氨蝶呤是治疗儿童......
