N6-methyladenosine相关论文
Prognostic Role and Potential Mechanisms of N6-methyladenosine-related Long Noncoding RNAs in Hepato
Background and Aims: Numerous studies have explored the important role of N6-methyladenosine (m6A) in cancer. Nonetheles......
METTL14 suppresses colorectal cancer progression via regulating N6-methyladenosine-dependent primary
Objective Colorectal cancer(CRC)is the third most common cancer and the fourth most fatal malignancy in the world....
Systematic analyses of m6A methylomes revealed pervasive site-specific regulation of m6A by RNA bind
N6-methyladenosine(m6A)is a reversible and dynamic RNA modification in eukaryotes.It plays important roles in a vari......
目前2型糖尿病(T2DM)及其并发症的发病机制仍未研究清楚。近年来一些报道表明，表观遗传学可能在T2DM及其并发症的发生、发展中起到......
原始生殖细胞(Primordial Germ Cells,PGCs)是生殖细胞的祖细胞,在生命延续的过程中至关重要。研究PGCs发生不仅对于了解精卵发生......
Longitudinal epitranscriptome profiling reveals the crucial role of N6-methyladenosine methylation i
N6-methyladenosine(m6A)represents the most abundantly occurring mRNA modification and is involved in the regulation of s......
The biological roles of N6 methylation of nucleic acids have been extensively studied.Adenine methylation of RNA is the ......
N6-Methyladenosine (m6A) modification is the most pervasive modification of human mRNA molecules.It is reversible via re......
,Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransfe
N6-methyladenosine (m6A),a ubiquitous RNA modification,is installed by METTL3-METTL14 complex.The structure of the heter......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的探究N6-甲基腺嘌呤(m6A)去甲基化酶ALKBH5与弱精症的相关性。方法收集精液标本30份,包括弱精症患者与健康者精液标本各15份,密......
N6-腺苷酸甲基化(m6A)修饰是病毒和真核生物RNA最丰富、最重要的内部修饰,在基因的转录后调控中起关键作用。m6A修饰调控RNA生命过......
The m6A methylation landscape stratifies hepatocellular carcinoma into 3 subtypes with distinct meta
Objective:Epigenetic aberration plays an important role in the development and progression of hepatocellular carcinoma(H......
目的:通过生物信息学工具探讨20个m6A调节基因在子宫内膜癌(UCEC)组织中的表达水平并筛选与预后有关的核心基因,阐明核心基因与免......
目的研究LIM域结合蛋白2(LDB2)在肺腺癌中的表达模式及作用。方法从mRNA和蛋白表达数据库中分析在肺腺癌中表达下调基因的交集。通......
N 6-甲基腺苷(N6-methyladenosine,m6A)是丰度最高的RNA表观遗传学修饰。本文介绍m6A修饰及相关调控蛋白m6A甲基转移酶、m6A去甲基......
The biological roles of N6 methylation of nucleic acids have been extensively studied.Adenine methylation of RNA is the ......
Background: N6-Methyladenosine(m~6A), the most prevalent modification in mammalian m RNA, plays important roles in numer......
The functional impact of modifications of cellular RNAs,including mRNAs,miRNAs and lncRNAs,is a field of intense study.T......
原发性肝癌是我国最常见的恶性肿瘤之一,其中85%~90%为肝细胞癌(HCC, hepatocellular carcinoma),对全国上报的2014年肿瘤登记数据......
