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From oral formulations to drug-eluting implants:using 3D and 4D printing to develop drug delivery sy
Since the start of the Precision Medicine Initiative by the United States of America in 2015,interest in personalized me......
Proteins and peptides have become a significant therapeutic modality for various diseases because of their high potency ......
Efficient non-or minimal-invasive administration of biologic medicines has remained as a long-standing objective of phar......
Delivery of bio-macromolecular therapeutics,an ideal stage for displaying the beauty of chemical art
While biologic medicines have been rapidly growing since 1980s,the advances of their administrating technologies are utt......
Fabrication of gelatin methacryloyl hydrogel microneedles for transdermal delivery of metformin in d
Injection therapy for diabetes has poor patient compliance,and the pain occurring at the site of subcutaneous injections......
Reverse immune suppressive microenvironment in tumor draining lymph nodes to enhance anti-PD1 immuno
The maturation of dendritic cells (DCs) and infiltration effector T cells in tumor-draining lymph node (tdLN) and tumor ......
目的探索不同微针对氨甲环酸体外经皮渗透的影响。方法采用高效液相色谱法测定氨甲环酸含量。采用改良Franz扩散池法,以离体猪皮为......
微针是一种具有微米尺度的经皮给药技术,从内部结构可分为实心与空心微针.制作微针的材料主要有硅、金属、聚合物等.微针增强了皮......
目的：将不锈钢微针阵列应用于经皮给药。考察离体大鼠皮肤经不同针形微针预处理相同时间、相同针形微针预处理不同时间后，模型药物鬼......
采用微针向生物体运送药物是经皮给药的重要方式，而微针的制备方法是其实现的关键。采用机械切割与化学湿法刻蚀相结合的方法研究制......
目的研究不同微针作用于猪皮对光甘草定搽剂体外透皮吸收的影响。方法采用HPLC和改良Franz扩撒池法，分别以实心微针和空心微针作用......
Background: The microneedle fractional RF handpiece used in our study (Intensif Handpiece, EndyMed Medical, Caesarea, Is......
Usefulness of Basic Fibroblast Growth Factor (bFGF) Loaded Dissolving Microneedles for Local Therapy
Purpose: The usefulness of dissolving microneedles (DMs) for local skin therapy by basic fibroblast growth factor (bFGF)......
Two-and Three-Layered Dissolving Microneedles for Transcutaneous Delivery of Model Vaccine Antigen i
Purpose: Comparison of transcutaneous immunization of ovalbumin (OA) between two-and three-layered dissolving microneedl......
[Objectives]To prepare curcumin solid dispersion(Cur SD)by the melting method,using povidone(PVP K30),polyethylene glyco......
