HYPOXIA相关论文
31. Antioxidant and hypoxia induce the human antioxidant response element-mediated expression of NAD
Background: NAD(P)H: quinone oxidoreductase 1 (NQO1) is an obligate two-electron reductase that is involved in protectio......
A smart O2-generating nanocarrier optimizes drug transportation comprehensively for chemotherapy imp
Drug transportation is impeded by various barriers in the hypoxic solid tumor,resulting in compromised anticancer effica......
Nitric oxide(NO)has emerged as an important signal molecule in plants,having myriad roles in plant devel-opment.In addit......
Effects of dissolved oxygen and nutrients from the Kuroshio on hypoxia off the Changjiang River estu
The intrusion of the Kuroshio into the East China Sea(ECS)affects the development of hypoxia off the Changjiang(Yangtze)......
目的:论证急性低氧血症对使用呼吸机辅助的呼吸衰竭患者中心静脉压(CVP)的影响。方法:回顾性分析危重患者医学信息数据库Ⅲ(MIMIC ......
目的:评价不同密度低温缺氧复氧大鼠心脏成纤维细胞(RCF)对心肌细胞损伤和细胞间偶联的影响。方法:体外培养RCF，采用随机数字表方法......
目的:评价hsa_circ_0008039和miR-484在人神经母细胞瘤(SK-N-SH)细胞氧糖剥夺-复糖复氧(OGD/R)损伤中的作用及其与线粒体分裂蛋白1......
目的:评价铁死亡在高脂高糖心肌细胞缺氧复氧损伤中的作用。方法:正常培养的H9c2心肌细胞，采用随机数字表法分为3组(n n＝20)：对......
目的:评价低温缺氧复氧时大鼠心肌成纤维细胞(RCF)对H9c2细胞缝隙连接蛋白43(Cx43)表达的影响。方法:体外培养的H9c2细胞，采用随机......
目的:探讨蛋白激酶Cβ2 (protein kinase Cβ2, PKCβ2）在高糖与缺氧/复氧（hypoxia/reoxygenation, HR）诱导的心肌细胞焦亡中的作用。......
目的:探讨缺氧条件下辛伐他汀(Sim)对体外培养的人视网膜色素上皮(RPE-19)细胞的影响及其可能机制.方法:将体外培养的人RPE-19细胞......
Photodynamic therapy (PDT) has emerged as a potential clinical strategy for tumor therapy. It can gener-ate reactive oxy......
Dynamics of bacterial communities during a seasonal hypoxia at the Bohai Sea:Coupling and response b
Marine bacterial community plays a vital role in the formation of the hypoxia zone in coastal oceans.Yet,their dynamics ......
研究以斑马鱼(Danio rerio)为研究模型,选择心脏和血管荧光标记的2个品系斑马鱼为实验材料,设定低氧和常氧2种水体溶氧条件,用荧光......
Hypoxia Inhibits Proliferation of Human Dermal Lymphatic Endothelial Cells via Downregulation of Car
Objective:Lymphatic endothelial cell(LEC)proliferation is essential for lymphangiogenesis.Hypoxia induces lymphangiogene......
目的:探究lncRNA KB-1980E6.3在乳腺癌干细胞干性维持中的作用及其分子机制研究。方法:（1）采用RNA-seq鉴定出人乳腺癌细胞株中低氧反......
Yishen Huoxue decoction(益肾活血方)attenuates unilateral ureter-ic obstruction-induced renal fibrosis and
OBJECTIVE:To investigate the effeicacy of Yishen Huoxue decoction (YSHX) on renal fibrosis induced by unilateral ureteri......
Hif-1α/Hsf1/Hsp70 signaling pathway regulates redox homeostasis and apoptosis in large yellow croake
Oxygen is an essential molecule for animal respiration,growth,and survival.Unlike in terrestrial environments,contaminat......
miR-140-3p enhanced the osteo/odontogenic differentiation of DPSCs via inhibiting KMT5B under hypoxi
Human dental pulp stem cells (DPSCs) have emerged as an important source of stem cells in the tissue engineering, and hy......
Objective:Kidney cancer is a group of cancers occurred in the kidney. Hypoxia is a condition characterized by insuffi-ci......
Tirapazamine encapsulated hyaluronic acid nanomicelles realized targeted and efficient photo-bioredu
Currently,architecting a rational and efficient nanoplatform combing with multi-therapeutic modalities is highly obligat......
Self-propelled nanomotor reconstructs tumor microenvironment through synergistic hypoxia alleviation
Solid tumors always exhibit local hypoxia,resulting in the high metastasis and inertness to chemotherapy.Reconstruction ......
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Ginsenoside Rb1 Ameliorates Autophagy of Hypoxia Cardiomyocytes from Neonatal Rats via AMP-Activated
Objective:To investigate whether ginsenoside-Rb1 (Gs-Rb1) improves the CoCl2-induced autophagy of cardiomyocytes via upr......
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Stroke is a leading cause of death worldwide.Up to one thousand potential drugs or interventions have been developed to ......
BDNF Overexpression Enhances the Preconditioning Effect of Brief Episodes of Hypoxia, Promoting Surv
Hypoxia causes depression of synaptic plasticity,hyperexcitation of neuronal networks,and the death of specific populati......
Aim: To evaluate the effect of chronic hypoxia on human spermatogenic parameters and their recovery time. Methods: Semin......
Vascular endothelial growth factor A, secreted in response to transforming growth factor-β1 under hy
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Upregulation of erythropoietin and erythropoietin receptor in castration-resistant progression of pr
Hypoxia-induced erythropoietin signaling plays an important role in tumor growth and invasion.In the present study,we in......
Over-starvation aggravates intestinal injury and promotes bacterial and endotoxin translocation unde
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Seasonal variation of manganese release from sediment of the monomictic lake.-A case study in the La
Enrichment of Mn and As in the surface of sediment caused by diagenetic process has been reported from various lakes in ......
Hypoxia Induced by Upconversion-based PDT:Towards High-effective Synergistic Bioreductive Therapy in
Local hypoxia in tumors is an undesirable consequence of photodynamic therapy(PDT)which will lead to greatly reduced eff......
本研究利用微囊化成骨细胞和低氧环境体外模拟支持脐血造血干/祖细胞扩增的微环境.采用聚电解质络合制囊法,将SD大鼠成骨细胞用明......
Accurate diagnosis of tumors and their pathological states could effectively improve the therapeutic outcomes.Magnetic r......
Hypoxia is a characteristic of most tumor and neurodegenerative diseases with low oxygen condition caused by numerous en......
Recombinant Metallothionein Fusion Proteins as Protective Therapeutics against Glucolipotoxicity, Hy
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Methylation-mediated silencing of miR-124 facilitates Chondrogenesis by Targeting NFATc1 under Hypox
Chondrogenic differentiation of mesenchymal stem cells was regulated by different pathways.Sox9 has been regarded as mas......
Bcakground: Both hypoxia and the marked increase of inflammatory cytokines are the common hallmarks of intervertebral di......
TheExperimentofCo-cultureMesenchymalStemCellswithUmbilicalVeinEndothelialCellsunderHypo
Objective Byco-cultureof hMSCsandHUVECsinhypoxia,simulateamicroenvironmentsimilartowhere transplantationofhMSCsfortreatm......
Hypoxia differentially regulates the metabolism of human nucleus pulposus cells under basal and IL-1
Objective: HIF-2α has been shown to exhibit robust expression in human nucleus pulposus (NP) tissue, regulating the met......
Investigation of Hypoxia Conditions Using Oxygen-Enhanced Magnetic Resonance Imaging Measurements in
Purpose The objective of this study was to investigate hypoxia conditions of glioma using oxygen-enhanced magnetic reson......
Zn2+isanessentialcomponentofmetalloproteinases,andisrequiredfortheiractivityincartilage;however,theeffectofZn2+onnucleus......
Evodiamine,has therapeutic potential in drug resistance by targeting HIF-1α in hypoxic microenvironm
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Reduction of ZNF24 inducing augment of VEGF-A stimulates angiogenesis in pancreatic cancer under hyp
Objective Angiogenesis,a ubiquitous biological behavior in human solid tumors,is crucial for the tumor to surmount the d......
HIF-1αmediateshypoxia-inducedexpressionofthechemokinereceptorCXCR4andcontributestometastasisinmanydifferentcancers.Weha......
