GABAAreceptor相关论文
Identification of a domain in the GABAA receptor δ subunit （S238-L277） that confers high agonist sen
＜正＞ GABA, the major inhibitory neurotransmitter in the mammalian brain, exertsmost of its effects by acting at GABAA rece......
Modulation of firing activity by endogenous GABAA receptors in the globus pallidus of MPTP-treated p
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Ethanol Increases Mechanical Pain Sensitivity in Rats via Activation of GABAA Receptors in Medial Pr
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objectives: Known as the major inhibitory neurotransmitter of GABA receptors in the brain, GABA is synthesized primarily......
In this study, one-trial step-through task has been applied to reveal the effect of prefrontal infralimbic cortex GABAA ......
Contribution of GABAA receptor-mediated activity to self-generated oscillations in hippocampal CA3-C
Objective Spontaneous oscillations in the hippocampus are believed to play important roles in hippocampus-dependent cogn......
Activation of GABAA receptors at axon initial segment suppresses action potential firing in neocorti
In addition to the distribution at somatodendritic compartments,GABAA receptors also express at the axon of excitatory p......
Arginine vasopressin modulation of GABAergic synaptic transmission in rat preoptic area of hypothala
It is well known that the preoptic area(POA)of hypothalamus,containing temperature-sensitive and-insensitive neurons,pla......
AT1 receptor blockade in the central nucleus of amygdala attenuates the effects of muscimol on sodiu
Evidence based on experimental animal studies indicates that the blockade of the GABAA receptors(GABAARs)in central nucl......
Properties of synaptic responses evoked by tactile stimulus in Purkinje cells in mice cerebellar cor
Sensory stimuli evoke responses in cerebellar Purkinje cells (PCs) via mossy fiber-granule cell pathway.However, the pro......
New compound YZG-330 augments pentobarbital induced sleep behaviors:involvement of Cl-channel activa
OBJECTIVE Insomnia is an extremely common symptom in modern society.We have demonstrated that YZG-330 which is a new mod......
Proper development of inhibitory GABAergic synapses is critical for establishing an excitatory/inhibitory balance in the......
2-guanidine-4-methylquinazoline acts as a novel competitive antagonist of A type γ-aminobutyric acid
The pentameric a type γ-aminobutyric acid receptors (GABAARs) are the major inhibitory neurotransmitter receptors in th......
Prediction of Binding Modes and Binding Affinities of Propanidid and AZD-3043 with the GABAA Recepto
Propanidid is an intravenous anesthetic with transient action and rapid recovery features,but it is clinically unaccepta......
Propofol differentially induces unconsciousness and respiratory depression through distinct interact
Propofol is the most commonly used intravenous anesthetic worldwide.It can induce loss of consciousness prior to the occ......
The key roles of 5Ile in the binding of fipronil with GABAA receptors from fruitfly and zebrafish, r
Fipronil, which act on insect GABAA receptor was an important insecticide for crop protection.However, the observed high......
目的研究溴氰菊酯(deltamethrin，DM)亚慢性染毒对小鼠学习记忆及海马组织γ-氨基丁酸A受体(GABAA)α1和γ2亚单位表达的影响。方法......
目的从黄芩地上部分中寻找活性成分.方法利用各种柱色谱(硅胶、Sephadex LH-20、D101大孔吸附树脂和聚酰胺)分离黄芩地上部分的活......
AIM: To investigate the role of endogenous γ-aminobutyric acid (GABA) in pancreatic exocrine secretion.METHODS: The iso......
目的 分析并确定一个全面性癫痫伴热性惊厥附加症(generalized epilepsy with febrile seizures plus,GEFS+)家系临床表型,并对其C......
用全细胞膜片箝记录技术在大鼠分离背根节神经元上观察预加多巴胺对ＧＡＢＡ－激活电流的调控作用。发现大部分受检细胞（４０／４７）对外加ＧＡＢＡ敏感。１０＾－６～１０＾－３ｍｏｌ／Ｌ ＧＡＢＡ引起一......
目的本研究旨在探讨印防已毒素和荷包牡丹碱对小鼠CO2激光痛阈的影响.方法 NIH小鼠105只,随机分为七组,每组15只.对照组,注射0.9%......
