mPFC相关论文
抑郁症严重威胁人类的生命健康,这种与应激相关的情绪障碍疾病已经造成极高的致残率和自杀率,使社会和家庭背负巨大的经济负担和精......
妊娠期阿片类药物使用已成为全球严重的公共卫生问题,妊娠期吗啡暴露可影响胎儿大脑发育。急性吗啡依赖大鼠模型可模拟人类的成瘾......
抑郁症是一种严重且容易反复发作的精神障碍疾病,预计到2020年将成为世界第二大致残类疾病,但是其具体发病机理尚不十分清楚。抑郁......
抑郁症是最常见的心境障碍疾病,具有发病率高、致残率高、负担重等特点。首先,发病率高,全球大概有3.5亿的抑郁症患者。在人的一生......
Forebrain-restricted knockout of rap1 genes facilitates the extinction of conditioned fear and enhan
We have previously shown that double knockout(KO)of rap1 genes(rap1a and rap1b)in forebrain led to impairment of auditor......
Stress has been found an important role in modulating behaviors.It is believed that acute and chronic stress have positi......
An antidepressant from Chinese herbs Improves the burst firing of medial prefrontal cortex induced b
Aim: Discovery of new antidepressants from traditional Chinese medicine is one of the promising field for the treatment ......
Effect of chronic methylphenidate exposure on NMDA receptor phosphorylation and expression in the me
Methylphenidate is widely used for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD), but the molecular m......
Chronic stress is among the most common environmental factors leading to the development of neuropsychiatric disorders.T......
Chronic morphine treatment selectively increases the effect of presynaptic D1 receptors on the excit
The study of the chronic morphine treatment-induced changes in neurocircuitry is of importance for understanding the mec......
An antidepressant from Chinese herbs improves the burst firing of medial prefrontal cortex induced b
Aim: To explore new antidepressants from traditional Chinese medicine is one of the promising field for the treatment of......
The effect of transcranial direct current stimulation in medial prefrontal cortex on the gratitude o
Gratitude is an important aspect of human sociality,which leads to benefits for both mental health and interpersonal rel......
The leading expectation-based theories of decision-making under risk were primarily developed to explain how people beha......
Objective:To investigate the effects of chronic unpredictable mild stress(CUMS)on perineuronal nets(PNNs)andγ-aminobuty......
期刊
目的:观察脑内同步灌流特异性呼吸链复合体Ⅳ抑制剂叠氮钠(sodium azide,NaN3)对大鼠腹内侧前额叶皮质(mPFC)和海马细胞外液中乙酰......
Objective: To investigate the effects of chronic unpredictable mild stress (CUMS) on perineuronal nets (PNNs) and γ-ami......
期刊
目的 探讨利他林改善注意缺陷多动障碍(ADHD)大鼠动物模型(SHR)注意定势转移能力的可能神经生化机制.方法 4周雄性SHR16只,分为SHR......
The medial prefrontal cortex (MPFC) of human adults is involved in attributing mental states to real human agents but no......
摘要：目的研究6-羟多巴胺（6-OHDA）损毁大鼠黑质致密部（sNc）后内侧前额叶皮层（mPFC）中锥体神经元NMDA受体敏感性的变化。方法应用在体细胞......
恐惧消退是指随着环境的变化,通过学习抑制以前的习得性恐惧的调节能力.这一过程包括重复暴露于条件刺激(conditioned stimulus,CS......
目的：研究肝癌模型大鼠内侧前额叶皮层（mPFC）GABA能中间神经元放电频率和放电形式的变化。方法：应用在体细胞外电生理学记录的方法观察......
目的研究6-羟多巴胺（6-OHDA）损毁大鼠黑质致密部（SNc）后内侧前额叶皮层（mPFC）中锥体神经元电活动增强及5-羟色胺（5-HT）1A受体敏感性下降与A......
目的研究肝性脑病（HE）模型大鼠内侧前额叶皮层（mPFC）GABA能中间神经元放电频率和放电形式的变化。方法应用在体细胞外电生理学记录的方......
目的研究帕金森病（PD）模型大鼠内侧前额叶皮层（mPFC）中γ-氨基丁酸（GABA）能中间神经元放电频率和放电形式的变化。方法应用在体细胞外电......
抑郁症,又称抑郁障碍,是临床精神科或心理科常见的一种慢性疾病,以持续情绪低落为其主要特征。抑郁症在中国大陆人群中属于高发疾......
目的探讨BDNF在缺糖缺氧复灌条件下对小鼠mPFC脑区胶质纤维酸性蛋白GFAP蛋白的影响。方法 2017年12月—2018年2月,徐州医科大学麻......
[背景]内嗅皮层(EC)在海马与新皮层中起到十分重要的连接作用,在老年痴呆(AD)早期,EC到海马的投射是最早受到攻击的环路,并与记忆......
共情是一种感知他人情绪状态的能力，在过去多属于心理学研究的范畴，近年来随着脑影像技术的发展，人们开始关注共情发生的神经结构基础......
目的:遥测海洛因诱导条件性位置偏爱(conditioned place preference,CPP)大鼠穿梭觅药潜伏期内侧前额皮层(medial prefrontal cort......
目的探讨脑源性神经生长因子(BDNF)在缺糖缺氧复灌条件下对mPFC脑区突触前膜蛋白Synapsin-1的保护作用。方法将18只小鼠随机分为正......
学习和记忆是大脑的基本功能,其中消退学习是生物体适应复杂环境变化的保障。许多脑疾病,如焦虑症,都与消退学习障碍密切相关。基......
目的:探究学习记忆中晚期巩固现象在可卡因潜伏心理渴求中的作用,以及表观遗传学机制。方法:利用可卡因自身给药潜伏心理渴求模型,......
