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Fatty acid oxidation and autophagy promote endoxifen resistance and counter the effect of AKT inhibi
Tamoxifen (TAM) is the first-line endocrine therapy for estrogen receptor-positive (ER+) breast cancer (BC).However,acqu......
The relationship between the CYP2D6 polymorphisms and endoxifen serum concentration in Chinese breas
Objective Background Endoxifen is the major mediator of tamoxifen effect and low endoxifen levels may be associated with......
目的:研究乳腺癌术后服用他莫昔芬(TAM)辅助治疗绝经前、雌激素受体(ER)阳性患者CYP2D6基因多态性与TAM活性代谢产物Endoxifen血药......
目的 建立HPLC-MS/MS法测定人体全血样品中他莫昔芬及代谢产物的浓度。方法 采用岛津LC210（A）高效液相色谱仪联用API3200D型三重四级......
