Enantioseparation相关论文
Simultaneous enantioseparation and simulation studies of atenolol,metoprolol and propranolol on Chir
Enantioseparation of three β-blockers,i.e.,atenolol,metoprolol and propranolol,was studied on amylose tris(3-chloro-5-m......
Pidotimod plays an important role in immunomodulation of human infection disease.Its systematic name is(4R)-3-(5-oxo-L-p......
A highly sensitive method for enantioseparation of fenoprofen and amino acid derivatives by capillar
...
手性除草剂的对映异构体间往往表现出不同的生物活性，而过多的使用会对生物与环境 产生巨大的风险。采用Sino-Chiral OJ 手性柱在超......
ENANTIOSEPARATIONS BY CAPILLARY ELECTROPHORESIS WITH HYDROXYPROPYL-β-CYCLODEXTRIN IMPRINTED POLYMERS
INTRODUCTION In nature,about half of the drugs in use are chiral compounds and only about 25%are administered as pure en......
Mathematical model of enantioseparation of chiral drugs with two stereogenic centers for elucidation
Chiral drugs with two stereogenic centers have four stereoisomers belonging respectively to two pairs of enantiomers.The......
Ultra High Sensitive Determine The Optical Impurities of Sitafloxacin by Capillary Electrophoresis w
In this paper,a robust chiral separation method for the separation of four enantiomers of sitafloxacinwas developed.Meth......
Oligomeric N-substituted glycines or "peptoids" with α-chiral, aromatic side chains can fold into well-defined helica......
Aptamers-based partial filling technique for enantioseparation and determination of DL-Tryptophan in
A novel, simple, reproducible method was reported in this study for the enantioseparation and determination of DL-Trypto......
Enantioseparation of three amino alcohols using Di-n-butyl L-tartrate-boric acid complex as mobile p
As it is well known that tartrate is a kind of widely used chiral selector in a great variety of enantioseparation of ch......
Many active compounds contain pyrrole thione structure which has some applicability in the biological field.We studied t......
Development and validation of HPLC methods for enantioseparation of mirtazapine enantiomers at analy
Mirtazapine is a recent noradrenergic and specific serotonergic antidepressant (NaSSA) drug, and used to treat moderatel......
Enantioseparation of phenylethanolamine derivatives by capillary electrophoresis employing sulfobuty
The use of CE methods for the separation of chiral compounds has become increasing popular in recent years.Cyclodextrins......
Design of new columns for capillary electrochromatography using a chiral stationary phases with poly
Capillary electrochromatography (CEC) is hybrid separation technique (combined advantages of both capillary eleetrophore......
Polysaccharides are the most abundant optically active polymers on the earth and can be easily modified to carbamate gro......
采用正相、反相和极性有机相3种分离模式,利用4种国产商品手性柱对65种药物进行手性拆分.4种固定相分别是纤维素-三( 3,5-二甲基苯......
本文通过对荣华二采区10...
Chiral extractant plays a key role in chiral extraction,and considerable efforts have been undertaken for the developmen......
利用L-谷氨酸苄酯开环聚合得到聚L-谷氨酸苄酯,对其进行表征,将聚L-谷氨酸苄酯溶于四氢呋喃后涂敷在3-氨丙基三乙氧基硅胶上制得液......
将海藻酸钠的乙酸溶液涂敷在3-氨丙基三乙氧基硅胶上,合成和表征了海藻酸钠涂敷手性固定相,以不同比例的正己烷/异丙醇为流动相,研......
合成了β-环糊精-对氯苯基氨基甲酸酯衍生物,并分别涂敷于氨丙基硅胶和硅胶表面,制得两种涂敷型β-环糊精-对氯苯基氨基甲酸酯手性......
正相条件下,在自制的涂敷型直链淀粉-三(环己基氨基甲酸酯)手性固定相上,直接拆分了九种不同类型的手性化合物,考察了流动相中极性......
Hollow fiber liquid-supported membrane technology for enantioseparation of racemic salbutamol by com
Enantioseparation of salbutamol solute was carried out in liquid-supported membrane by using a polyvinylidene fluoride h......
Biomacromolecules including protein and nucleic acids are considered as promising chiral selectors in the fields of enan......
Enantioseparation of some Racemic Compounds on Cellulose Tris (3,5-dimethylphenylcarbamate) Chiral S
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Preparation and chiral recognition of a novel chiral stationary phase for HPLC,based on mono(6A-N-1-
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
以三嵌段聚醚P123为模板，四乙氧基硅烷为前驱体，在强酸性条件下合成了高比表面积、大孔径、微米级的球形SBA-15．将纤维素-三（3，5-二甲基......
COVALENTLY BONDING CHIRAL POLYURETHANE ON AMINATED SILICA GEL: A NEW STRATEGY TO PREPARE CHIRAL STAT
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
首次采用结合区段灌注技术及场放大进样的毛细管电泳技术对山莨菪碱四种异构体进行了拆分。详细探讨了溶液pH值、拆分试剂含量、分......
Enantioseparation of some Racemic Compounds on Cellulose Tris (3,5-dimethylphenylcarbamate) Chiral S
Seven chiral compounds were resolved on cellulose tris (3,5-dimethylphenylcarbamate) chiral stationary phase (CDMPC-CSP)......
Gas Chromatographic Enantiomer Separation of Cyclopropane Derivatives on Three 2, 6-Di-O-allyl-3-O-a
Eight pairs of enantiomers of cyclopropane derivatives were resolved on capillary gas chromatographic columns using thre......
COVALENTLY BONDING CHIRAL POLYURETHANE ON AMINATED SILICA GEL: A NEW STRATEGY TO PREPARE CHIRAL STAT
Two polyurethanes of different molecular weights were prepared by the copolymerization of phenyl diisocyanate and diisop......
Enantioseparation of Dencichine and D-Isomer on L-Cysteine Derivative Phase by Ligand-exchange Chrom
The enantioseparation of dencichine and its D-isomer was achieved on a novel chiral stationary phase via coating N-(2-hy......
Enantioseparation of Aminoglutethimide by High-speed Counter current Chromatography Using Carboxymet
Enantioseparation of aminoglutethimide was performed by high-speed counter-current chromatography with a two-phase syste......
Preparation and chiral recognition of a novel chiral stationary phase for HPLC,based on mono(6A-N-1-
A novel chiral stationary phase (CSP) was prepared by immobilizing mono(6A-N-1-(2-hydroxyl)-phenylethylimino-6A-deoxy)-......
Hollow fiber liquid-supported membrane technology for enantioseparation of racemic salbutamol by com
Enantioseparation of salbutamol solute was carried out in liquid-supported membrane by using a polyvinylidene fluoride h......
彩用高效毛细管电泳技术，以β－环糊精或其衍生物为手性选择剂分离了五种药物光学对映体；优化了背景电解质的ｐＨ值和手性选择剂的浓度；研究......
α-氨基酸是具有重要生理功能和结构功能的生物小分子,同时也是重要的化工原料。综述了α-氨基酸及其衍生物在农药合成中的研究及......
使用自行设计的毛细管电泳柱端电导检测系统，对甲霜灵对映体进行了拆分。着重研究了缓冲溶液浓度和酸碱度、手性拆分剂（β-CD）分离高......
综述了高效液相色谱（HPLC）手性固定相法（CSP）、手性流动相添加剂法（CMP）在拟除虫菊酯类农药手性分离中的研究应用；其中重点介绍了CSP，包括P......
在对称C18高效液相色谱柱上,采用手性配体流动相法对D,L-色氨酸对映体进行了拆分.实验结果表明:利用泵前预混的方式,以手性配体试......
采用毛细管区带电泳模式,以β-环糊精为手性选择剂分离了药物扑尔敏的光学对映体.考察了在不同背景电解质 pH 值尤其是较低 pH 值......
建立柱前衍生化-毛细管气相色谱法分离2，5-己二醇对映体的方法。用S-（-）-α-苯乙基异氰酸酯与外消旋2，5-己二醇反应，生成相应的衍生物在......
报道了以未涂层融硅石英毛细管(50 cm×75 μm)为分离柱,5 mmol/L NaOH+10 mmol/L Citric acid +3 mmol/L H3BO3+10 mmol/L β......
目的探讨自由基引发剂对β-环糊精（β-CD）毛细管整体柱手性药物拆分能力的影响。方法采用水溶性引发剂2,2＇-偶氮二异丁腈脒二盐酸盐（AI......
目的 建立一种高效液相色谱法分离佐米曲普坦对映体。方法 采用Chiralcel OJ色谱柱，以正己烷-乙醇-二乙胺（85：15：0．2）为流动相，检测波长22......
目的建立西多福韦对映体的拆分及异构体含量的反相高效液相色谱法测定。方法色谱柱为Intertsil ODS-3柱（4．6mm×250mm，5μm），以7．89m......
目的研究盐酸坦洛新对映体在纤维素衍生物及蛋白质固定相上的保留行为,优化色谱条件.方法采用Chiralcel OJ,Chiralcel OD-RH和Chir......
