BISPHOSPHONATES相关论文
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One-Pot Synthesis of Novel 1,2,3-Triazole Containing Bisphosphonates via the Controlled Michael-Type
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Purpose: Bisphosphonates are well-investigated antiresorptive medications,approved as first-line drugs for osteoporosis ......
Relative Curative Effects of Bisphosphonates in Renal Transplant Recipients with Osteopenia:A System
Background:To estimate relative curative effects and safety of four different bisphosphonates for ameliorating osteopeni......
Effectsofbisphosphonatesprophylactictreatmentofrenal transplant-associatedbonelossinthef
目的：肾移植相关骨病——特别是骨质疏松，是一种常见的并发症严重影响患者的生活质量。二膦酸盐类药物——作为一大类抗骨质疏松的一......
Doseeffectivenessrelationshipsdeterminingtheefficacyofibandronateformanagementofosteoporo
Objective: The purpose of this study was to perform a metaanalysis on the efficacy of ibandronate by evaluating the effe......
Experiments and synthesis of bone-targeting epirubicin with the water-soluble macromolecular drug de
Epirubicin(EPI) is a broad spectrum antineoplastic drug,commonly used as a chemotherapy method to treat osteosarcoma. Ho......
BisphosphonatesforPreventingOsteopeniainRecipientsofKidneyTransplant:ASystematicReviewof
Context:Osteopenicosteoporoticsyndromerepresentsabonecomplicationmostlyrelatedtorenaltransplantation.However,thereisnoco......
Pharmacogenetics of medication-related osteonecrosis ofthe jaw:a systematic review and meta-analysis
Objective Bisphosphonates are commonly administered as bone-specific anti-resorptive agents to patients who at increased......
Nitrogen-containing bisphosphonic acids and their salts (N-BP) represent an important class of phosphorus compounds poss......
Efficacy and Safety of Different Bisphosphonates for Bone Loss Prevention in Kidney Transplant Recip
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成骨不全(osteogenesis imperfecta，OI)是一种由间充质组织发育不全、胶原形成障碍引起的先天性遗传性结缔组织疾病。其特征表现为......
Bisphosphonates are a class of drugs used as the mainstay of treatment for osteoporosis.Bisphosphonates function by bind......
Determination of bisphosphonates anti-resorptive properties based on three forms of ceramic material
There is a strong need to search for more effective compounds with bone anti-resorptive properties,which will cause fewe......
本综述介绍了BP(双膦酸盐)辅助治疗CPT(先天性胫骨假关节)的进展，综合了近年来国外对该研究的文章，其中包括基础研究及临床研究，并详......
目的评价狄诺塞麦与双膦酸盐类药物治疗糖皮质激素性骨质疏松患者疗效及安全性比较。方法通过检索CNKI、CBM、VIP、万方、Pubmed、......
Determination of bisphosphonates anti-resorptive properties based on three forms of ceramic material
There is a strong need to search for more effective compounds with bone anti-resorptive properties,which will cause fewe......
目的 观察二膦酸盐对大鼠佐剂性关节炎中关节软骨的影响,探讨其对软骨的保护作用.方法 将80只7周龄的Lewis雌鼠随机平均分为对照组......
目的：运用Meta分析方法研究双膦酸盐辅助手术对降低骨巨细胞瘤复发的影响,评价双膦酸盐在骨巨细胞瘤外科治疗中的作用。方法收集已......
Hypercalcaemia after treatment with denosumab in children:bisphosphonates as an option for therapy a
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Bacterial biofilms have emerged as potential critical triggers in the pathogenesis of bisphosphonate(BP)-related osteone......
Clinical Analysis of Bisphosphonates Treatment on Bone Metastases and Hypercalcemia of Malignancy in
Objective: To evaluate the efficacy and toleration of bisphosphonates therapy in patients with bone metastases and hyper......
Efficacy and Safety of Different Bisphosphonates for Bone Loss Prevention in Kidney Transplant Recip
Background:Mineral and bone disorder is one of the severe complications in kidney transplant recipients (KTRs).Previous ......
Failure to fire after an electrical injury - A complex syndrome in a soldier：complex regional pain s
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
A multicenter, retrospective epidemiologic survey of the clinical features and management of bone me
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 了解大剂量帕米膦酸二钠治疗前列腺癌骨转移疼痛的疗效及安全性.方法 将100例确诊为前列腺癌骨转移并伴骨痛的患者分为大剂......
Clinical Analysis of Bisphosphonates Treatment on Bone Metastases and Hypercalcemia of Malignancy in
Objective: To evaluate the efficacy and toleration of bisphosphonates therapy in patients with bone metastases and hyper......
目的:系统评价二膦酸盐对正畸治疗中牙根吸收的影响。方法:检索Pub Med等数据库中关于二膦酸盐对正畸治疗中牙根吸收影响的随机对......
目前骨质疏松骨折的治疗已取得长足进步.双膦酸盐为人工合成的焦磷酸盐类似物,是目前使用最广泛的抗骨质疏松药;狄诺塞麦是一种新......
目的：运用Meta分析和试验序贯分析（TSA）的方法探讨复方苦参注射液（CKI）联合双膦酸盐（BPs）辅治恶性肿瘤骨转移性疼痛的安全性和有效性。方......
目的探讨Ⅱ~Ⅲ期双膦酸盐相关颌骨坏死的手术治疗经验。方法Ⅱ~Ⅲ期双膦酸盐相关颌骨坏死患者29例,随访6个月以上,观察手术效果。......
骨质疏松症是一种全身代谢性疾病,双膦酸盐已被证实在提高骨密度和降低骨折风险方面有显著疗效,是目前临床上治疗骨质疏松症的一线......
目的了解老年女性骨质疏松性骨折患者手术后应用双膦酸盐的临床反应,分析常见不良反应的相关特点。方法收集苏州大学附属第二医院......
目的分析服用双磷酸盐药物对骨质疏松的患者行口腔外科手术后发生的感染,控制围手术期相关药物的使用。方法采用回顾性研究方法对......
目的通过实验观察阿仑膦酸钠联合辛伐他汀对骨质疏松大鼠骨折愈合的影响。方法成年雌性SD大鼠50只，随机分为5组：（A）假手术对照组；（B）去势......
牙周炎是一种由致病菌引起的炎症破坏性疾病，可造成包括牙槽骨吸收在内的一系列牙周组织破坏。双磷酸盐类（BPs）药物具有调节骨吸收、......
背景：双磷酸盐类药物对关节置换翻修发生率的疗效尚不明确.目的：评价术前或术后较长时间应用双磷酸盐类药物对降低全膝或全髋关节置......
背景：目前研究认为骨折术后应用双膦酸盐类药物不会影响骨折的愈合,但关于合理应用双膦酸盐类药物的最佳起始时间尚无定论。目的：探......
治疗基于 androgenic 剥夺是许多前列腺癌症病人接受的标准治疗之一。而且，它的使用与局部性的前列腺癌症在病人为这治疗由于指示的......
Best known for their anti-resorptive activity in bone,bisphosphonates （BPs） have generated interest aspotential antineopla......
目的探讨双磷酸盐相关性颌骨坏死（BONJ）的临床特点和预防对策。方法收集2006年1月至2010年12月诊治的BONJ患者临床数据进行回顾性分......
目的：分析恶性肿瘤伴高钙血症患者的临床诊治特点以及预后情况。方法：回顾性分析我科2004年1月-2008年6月收治的22例晚期恶性肿瘤合......
目的：探讨双膦酸盐作为辅助治疗方法降低四肢骨巨细胞瘤复发率的可行性。方法：2001年2月．2007年8月我院及香港中文大学威尔士亲王医院......
目的：研究二膦酸盐对强直性脊柱炎继发骨质疏松患者血清骨代谢指标、骨密度及多项基质金属蛋白酶（MMP）的影响。方法：选取我院2009年10......
目的:探讨正畸治疗中应用二膦酸盐对牙根吸收及牙移动的影响.方法:选取2014年8月—2016年8月我院收治的牙根发育不良的患者120例,......
目的 探讨早期静脉应用双磷酸盐对晚期前列腺癌进展及骨转移发生时间的影响。方法 随机选择2014年12月—2016年12月期间该院收治的......
双膦酸盐的抗骨吸收机制目前研究比较明确，目前已成为治疗恶性肿瘤骨转移的标准药物。然而，越来越多的体内外临床前实验表明，双膦酸盐......
