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Pathogenesis of RON receptor tyrosine kinase in cancer cells： activation mechanism, functional cross
[期刊论文] 作者：Ming-Hai Wang,Ruiwen Zhang,Yon,
来源：生物医学研究杂志：英文版 年份：2013
RON 受体酷氨酸 kinase，遇见的 proto-oncogene 家庭的一个成员，一个病原的因素在肿瘤恶意被含有。明确地，在 RON 发信号的错误导致增加的癌症细胞生长，幸存，侵略， angiogenesis，和...
[期刊论文] 作者：Ming-hai WANG,Hang-ping YAO,Yong-qing ZHOU,
来源：中国药理学报（英文版） 年份：2006
Recepteur d’origine nantais (RON) belongs to a subfamily of receptor tyrosine kinases (RTK) with unique expression patts and biological activities. RON is acti...
Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional cross
[期刊论文] 作者：Ming-Hai Wang,Ruiwen Zhang,Yong-Qing Zhou,Hang-Ping Yao,,
来源：The Journal of Biomedical Research 年份：2013
The RON receptor tyrosine kinase,a member of the MET proto-oncogene family,is a pathogenic factor implicated in tumor malignancy.Specifically,aberrations in RON...
Material removal mechanisms and characteristics of potassium dihydrogen phosphate crystals under nan
[期刊论文] 作者：Ning Hou,Yong Zhang,Liang-Chi Zhang,Ming-Hai Wang,
来源：先进制造进展（英文版） 年份：2021
Potassium dihydrogen phosphate (KDP) crystals are important materials in high-energy laser systems.However,because these crystals are brittle and soft,machining-induced defects often emerge in KDP compo-nents.This study aimed to investigate......
Therapeutic Evaluation of Monoclonal Antibody-Maytansinoid Conjugate as a Model of RON-Targeted Drug
[会议论文] 作者：Hang-Ping Yao,Liang Feng,Jianwei Zhou,Ruiwen Zhang,Ming-Hai Wang,
来源：浙江省免疫学会第十次学术大会 年份：2016
Aberrant expression of the RON receptor tyrosine kinase,a member of the MET proto-oncogene family,contributes significantly to pancreatic cancer tumorigenesis and chemoresistance.Here we validate RON...
,Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in c
[期刊论文] 作者：Ming-Hai WANG,Snehal S PADHYE,Sunny GUIN,Qi MA,Yong-qing ZHOU,
来源：中国药理学报（英文版） 年份：2010
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Biological evaluation of antibody-maytansinoid conjugates as a strategy of RON targeted drug deliver
[会议论文] 作者：Liang Feng,Hang-Ping Yao,Yong-Qing Zhou,Jianwei Zhou,Ruiwen Zhang,Ming-Hai Wang,
来源：浙江省免疫学会第十次学术大会 年份：2016
Background: Aberrant expression of the RON receptor tyrosine kinase,a member of the MET proto-oncogene family,in breast cancer and non-small cell lung cancer (NSCLC) has therapeutic implication.Here w...
Efficacy of Anti-RON Antibody Zt/g4-Drug Maytansinoid Conjugation (Anti-RON ADC) as a Novel Therapeu
[会议论文] 作者：Liang Feng,Hang-Ping Yao,Wei Wang,Yong-Qing Zhou,Jianwei Zhou,Ruiwen Zhang,Ming-Hai Wang,
来源：浙江省免疫学会第十次学术大会 年份：2016
Purpose: The receptor tyrosine kinase RON is critical in epithelial tumorigenesis and a drug target for cancer therapy.Here,we report the development and therapeutic efficacy of a novel anti-RON antib...
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