在12例可疑高凝状态的病人中,以维生素B6体外处理血小板后测定ADP及胶原诱导的血小板聚集;在7例同类病人中测定口服维生素B6前后ADP及胶原诱导的血小板聚集,维生素B6用量每日4mg／kg×10天。结果显示.在体内、外试验中。维生素B6对ADP及胶原诱导的血小板聚集均有显著抑制作用。值得深入研究维生素B6作为一种新的抗血小板药物的临床应用前景。 Among 12 patients with suspected hypercoagulable state, ADP and collagen-induced platelet aggregation were measured after in vitro treatment of platelets with vitamin B6; ADP before and after oral administration of vitamin B6 and collagen-induced platelet aggregation were measured in seven similar patients, the amount of vitamin B6 Day 4mg / kg × 10 days. The results show that in vivo and in vitro tests. Vitamin B6 has a significant inhibitory effect on ADP and collagen-induced platelet aggregation. It is worth further studying the clinical application of vitamin B6 as a new antiplatelet drug.