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目的了解上海市奉贤区泰日社区大肠癌筛查情况,探讨大肠癌筛查效果。方法按照《上海市社区居民大肠癌筛查实施方案》,对50~79岁奉贤区泰日社区常住居民采用危险度评估问卷调查和大便隐血试验(FOBT)相结合的方法进行初筛,对初筛阳性的人群进行电子肠镜检查。结果在参加大肠癌筛查的2 643人中,确定初筛阳性者995例,阳性率为37.6%。其中522例进行了肠镜检查,肠镜检查率为52.46%。检出病变117例,病变检出率为22.41%,其中男性检出率为31.28%,女性检出率为16.40%,差异有统计学意义(χ2=16.01,P<0.01);筛查出大肠癌3例,大肠腺瘤79例,非腺瘤性息肉35例。结论危险度评估和FOBT相结合的筛查方法可以有效检出早期大肠癌和癌前病变,对于降低大肠癌的死亡率和发病率具有重要意义;泰日社区大肠癌检出率相对较高,病变检出率男性高于女性,且随着年龄的增长而升高,应着重加强重点人群的大肠癌防治工作。
Objective To investigate the screening of colorectal cancer in Thai-Japanese community in Fengxian District of Shanghai and to explore the screening effect of colorectal cancer. Methods According to the Implementation Plan of Colorectal Cancer Screening among Community-based Residents in Shanghai, 509-year-old residents living in Tai-Ri community in Fengxian District were initially screened by risk assessment questionnaire and fecal occult blood test (FOBT) Screen positive people for colonoscopy. Results Of the 2 643 persons who participated in the screening of colorectal cancer, 995 were positive for primary screening, the positive rate was 37.6%. Of these, 522 had colonoscopy, with a colonoscopy rate of 52.46%. 117 lesions were detected, the detection rate of lesions was 22.41%, of which the detection rate was 31.28% in males and 16.40% in females, the difference was statistically significant (χ2 = 16.01, P <0.01) 3 cases of cancer, 79 cases of colorectal adenoma, 35 cases of non-adenomatous polyps. Conclusion The combination of risk assessment and FOBT screening method can effectively detect early colorectal cancer and precancerous lesions, which are of great significance for reducing the mortality and morbidity of colorectal cancer. The detection rate of colorectal cancer in Thai-Japanese community is relatively high, Lesion detection rate of men than women, and increased with age, we should focus on strengthening the prevention and treatment of colorectal cancer in key populations.