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目的：研究麝香保心丸的舒张血管作用及可能的机制。方法：将离体大鼠动脉环随机分成正常组，去内皮组２组（共为６对动脉环，组内比较用自身对照，组间比较用配对对照）。用去甲肾上腺素诱导动脉环收缩后，加入麝香保心丸，记录反应。结果：麝香保心丸对正常组，去内皮组动脉环均有舒张作用（Ｐ＜０．０１），其效应呈剂量依赖；且其对正常组的舒张作用较去内皮组强（Ｐ＜０．０１）。结论：麝香保心丸具有舒张血管的效应，其机制可能有直接及内皮依赖的舒张血管２种作用。
Objective: To study the diastolic vascular effect and possible mechanism of Shexiang Baoxin Pill. METHODS: The isolated rat artery rings were randomly divided into normal group and deendothelial group 2 group (a total of 6 pairs of arterial rings were used. The group was compared with its own control and the paired controls were compared between groups). After inducing contraction of the aortic rings with norepinephrine, add Ruoxiang Baoxin Pills and record the reaction. RESULTS: Qixiang Baoxin Pill had a relaxing effect on the arterial rings in the normal and denervated groups (P<0.01). Its effect was dose-dependent, and its relaxing effect on the normal group was stronger than that on the denervated group (P<0). .01). Conclusion: Shexiang Baoxin Pill has the effect of relaxing blood vessels. The mechanism may be direct and endothelium-dependent dilation of blood vessels.