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通过对120例非胰岛素依赖型糖尿病患者详细的牙周检查,分析牙周病的发生率与糖尿病病程、血糖水平及微血管并发症的关系,并对部分患者牙龈组织行透射电镜观察。结果表明,糖尿病病程及微血管并发症的存在与牙周病的发生率有关(P<0.01),而人院时空腹血糖水平与其无关(P<0.05)。牙龈超微结构观察显示浆细胞变性严重、毛细血管基底膜增厚是糖尿病牙周病不同于非糖尿病牙周病的特征。提示糖尿病牙周病是糖尿病微血管病变的一个表现,免疫功能下降及毛细血管病变是糖尿病易患牙周病的原因之一。通过对牙周病的观察及牙龈活检,可对全身微血管病变进行初步评价。
Through a detailed periodontal examination of 120 cases of non-insulin-dependent diabetes mellitus, the relationship between the incidence of periodontal disease and the duration of diabetes, blood glucose levels and microvascular complications were analyzed. The gingival tissues of some patients were examined by transmission electron microscopy. The results showed that the duration of diabetes mellitus and microvascular complications were related to the incidence of periodontal disease (P <0.01), while the level of fasting blood glucose in hospital did not correlate with it (P <0.05). Ultrastructural observation of gingiva showed severe degeneration of plasma cells and thickening of capillary basement membrane characterized by periodontal disease of diabetes different from non-diabetic periodontal disease. Tip periodontal diabetes is a manifestation of diabetic microangiopathy, decreased immune function and capillary lesions is one of the causes of diabetic susceptibility to periodontal disease. Through the observation of periodontal disease and gingival biopsy, a preliminary evaluation of systemic microvascular disease.