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采用电阻抗法和光电比浊法分别测定了血瘀证缺血性心脏病患者的血小板聚集活性,结果显示全血及血浆血小板聚集率均有所增高。继而采用光电比浊法和放射免疫法对血瘀证缺血性脑卒中患者同步检测血小板聚集活性、聚集后β-血栓球蛋白(β-TG)释放量以及血浆β-TG 含量。结果表明,体外血小板聚集率和随之产生的β-TG 释放量并未显示一定的相关性,仅仅检测血小板聚集率有时并不能反映其活性程度。脑卒中急性期主要表现为聚集后β-TG 释放量以及血浆β-TG 含量明显增高,恢复期血小板几种活性指标虽有所改善,但仍较健康组异常增高。
The platelet aggregation activity of blood-stasis patients with ischemic heart disease was measured by electrical impedance spectroscopy and nephelometry. The results showed that the platelet aggregation rate of whole blood and plasma increased. Subsequently, the turbidimetric and radioimmunoassay methods were used to detect platelet aggregation activity, β-thrombin (TG) release and β-TG content in blood stasis patients with ischemic stroke. The results showed that in vitro platelet aggregation rate and subsequent release of β-TG did not show a certain correlation, only the detection of platelet aggregation rate sometimes does not reflect the degree of activity. In the acute phase of stroke, the release of β-TG and the content of β-TG in plasma were significantly increased. Although the activity indexes of platelet in recovery phase were improved, they were still higher than those in healthy group.