论文部分内容阅读
1917年,德国医生Alfred Nissle从一名士兵的粪便中第一次分离出无致病性的大肠埃希菌E.colinissle 1917(EcN),这位士兵在一次严重的志贺菌爆发中未患肠炎。其后,各种研究证实了EcN的益生菌特性并促进其在临床中的应用。
In 1917, the German doctor Alfred Nissle first isolated a nonpathogenic E. coliinselle 1917 (EcN) from a man’s excrement. The soldier was unaffected by a serious Shigella attack enteritis. Since then, various studies have confirmed the characteristics of EcN probiotics and promoted their clinical application.