一、前言脂质过氧化作用(Lipid peroxidation,简称LPO)原指脂肪,油等在空气中自动氧化酸败的现象。实质上是脂质中多元不饱和脂肪酸受氧化作用形成多元不饱和脂肪酸过氧化物的过程。机体内由于酶的和非酶的脂质的氧化反应也可以生成过氧化脂质。已经确认体内脂质过氧化作用的机制是自由基引发的链反应。由于机体内存在一系列的保护系统:如谷胱甘肽过氧化物酶(GSH-PX),维生素E,过氧化氢分 I. Introduction Lipid peroxidation (referred to as LPO) originally refers to the fat, oil and other auto-oxidative rancidity in the air. In essence, polyunsaturated fatty acids in the lipid are oxidized to form polyunsaturated fatty acid peroxide. Lipid peroxides can also be generated in the body due to the oxidation of both enzymatic and non-enzymatic lipids. It has been confirmed that the mechanism of lipid peroxidation in vivo is free radical-initiated chain reaction. As the body there is a series of protection systems: such as glutathione peroxidase (GSH-PX), vitamin E, hydrogen peroxide points