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中老年肾病综合征(NS)患者通常存在一定程度的肾功能不全和严重的低蛋白血症,目前为止尚无有效的治疗方法。输注白蛋白及其它胶体渗透液已被证实会带来肾小管和/或间质的进一步损害。本文采用前瞻性方法,采用低蛋白质饮食(LPD)加α-酮酸治疗中老年NS,发现该方法能有效纠正低蛋白血症,保护肾功能,且不发生或加重营养不良、贫血等症状。1 材料与方法共8例患者,男6例,女2例,年龄48～74岁,均为本院2000年2月至2001年1月之间的住院病人。8例患者中,原
In elderly patients with nephrotic syndrome (NS), there is usually some degree of renal insufficiency and severe hypoproteinemia, so far there is no effective treatment. Infusion of albumin and other colloidal permeates has been shown to cause further damage to the tubules and / or interstitium. In this study, we prospectively adopted a low-protein diet (LPD) plus alpha-keto acid to treat middle-aged and elderly NS. We found that this method can effectively correct hypoproteinemia and protect renal function, and does not cause or aggravate malnutrition and anemia. 1 Materials and Methods A total of 8 patients, 6 males and 2 females, aged 48 to 74 years, were hospitalized from February 2000 to January 2001 in our hospital. 8 patients, the original