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肿瘤组织比机体能更有效地夺取氨基酸,目前临床各种氨基酸液均促进肿瘤生长,利用不平衡氨基酸,可达到抑制肿瘤生长的同时又改善机体的营养状况。大剂量精氨酸能抑制肿瘤生长;亮氨酸能增强去缬氨酸的抑瘤效应,并且能改善宿主的营养状况;蛋氨酸缺乏,将对抗肿瘤药物起着“增效剂”的作用;去缬氨酸的不平衡氨基酸抑瘤效果最为显著;谷氨酰胺浓度下降则肿瘤生长受抑制;谷氨酰胺与天冬酰胺其拮抗剂由于阻碍核酸代谢而被试用于抑制癌的增殖。针对不同类型的肿瘤制定相应的不平衡氨基酸,能更有效地抑制肿瘤生长,并改善机体营养。
Tumor tissues can seize amino acids more effectively than the body. At present, all kinds of amino acids in clinical medicine promote the growth of tumors. Using unbalanced amino acids can inhibit tumor growth and improve the nutritional status of the body. High doses of arginine can inhibit tumor growth; leucine can enhance the anti-tumor effect of valine and improve the nutritional status of the host; lack of methionine will play a role of “synergist” in the anti-tumor drugs ; Valine unbalanced amino acid inhibition effect is the most significant; glutamine concentration decreased tumor growth inhibition; glutamine and asparagine antagonists due to the inhibition of nucleic acid metabolism was tried to inhibit cancer proliferation. For different types of tumors to develop the corresponding imbalance of amino acids, can more effectively inhibit tumor growth, and improve body nutrition.