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充血性心力衰竭或急性心肌梗塞时给予血管扩张剂减轻左心室负荷,可使心脏功能获得改善。但是,各种血管扩张药物是否具有各自的特征,可在不同的临床情况下提供有关的益处,则尚不清楚。为此,作者对29例急性心肌梗塞后24小时内的患者进行了硝普钠、酚妥拉明和硝酸甘油静脉滴注的血液动力学作用比较。为了有共同的比较基础,原来血压正常的患者调节药物滴速使平均动脉压下降至80毫米汞柱左右;对有高血压的患者则维持在90～100毫米汞柱。
Congestive heart failure or acute myocardial infarction given vasodilator to reduce left ventricular load, can improve cardiac function. However, it is unclear whether various vasodilators have their own characteristics and provide the relevant benefits in different clinical situations. To this end, the authors compared the hemodynamic effects of intravenous infusion of sodium nitroprusside, phentolamine and nitroglycerin in 29 patients within 24 hours of acute myocardial infarction. In order to have a common comparative basis, the original normotensive patients to adjust the drug drip rate so that the average arterial pressure dropped to about 80 mm Hg; for patients with hypertension remained at 90 to 100 mm Hg.