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卵透明带糖蛋白-3(ZP3)一直被认定为包括帽猴(Macacaradiata)和人类在内许多哺乳动物物种的第一精子受体。已有实验证明杆状病毒表达的糖基化帽猴重组ZP3(r-bmZP3)与帽猴精子共孵育的场合引发了顶体胞吐作用,而大肠杆菌表达的重组bmZP3蛋白未能产生此效果。不过也有实验表明大?
Zona pellucida glycoprotein-3 (ZP3) has long been recognized as the first sperm receptor in many mammalian species, including Macacaradiata and humans. It has been experimentally demonstrated that the baculovirus-expressed glycosylated caprine recombinant ZP3 (r-bmZP3) co-incubated with caprine sperm elicited acrosomal exocytosis whereas the recombinant bmZP3 protein expressed in E. coli failed to produce this effect . But there are experiments show that big?