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目的 :分析 1976年 5月～ 1999年 10月 36例多发性骨髓瘤 ( MM)患者可能影响生存的因素。方法 :根据入院时的临床和实验室记录 ,应用 L ogrank和 COX回归分析对有关因素作单因素和多因素分析 ,并绘制Kaplan- Meier生存曲线。结果 :单因素分析发现 MM患者的生存与年龄、临床分期、骨髓浆细胞百分数 ( BMPC)、血红蛋白 ( Hb)、血清白蛋白 ( Alb)及化疗结果之间有显著相关性 ( P <0 .0 5或 <0 .0 0 1) ,多因素分析显示各因素无统计学意义。结论 :年龄、临床分期、BMPC、Hb、Alb和化疗结果与 MM患者的生存有关
Objective: To analyze the possible influencing factors of survival in 36 patients with multiple myeloma (MM) from May 1976 to October 1999. METHODS: Based on clinical and laboratory records at admission, L ogrank and COX regression analyzes were used to perform univariate and multivariate analysis of the relevant factors and to plot Kaplan-Meier survival curves. Results: Univariate analysis showed that there was a significant correlation between survival and age, clinical stage, bone marrow plasma cell percentage (BMPC), hemoglobin (Hb), serum albumin (Alb) 5 or <0 0 01), multivariate analysis showed that the various factors were not statistically significant. CONCLUSIONS: Age, clinical stage, BMPC, Hb, Alb, and chemotherapy outcomes correlated with the survival of patients with MM