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目的 观察硝酸甘油加肝素静点对急性心肌梗死的止痛效果。方法 将553例急性心肌梗死病人随机分为两组:单独用硝酸甘油组(Ⅰ组)和硝酸甘油加肝素组(Ⅱ组),观察用药后6h内、7h～12h、13h～24h内两组病人的胸痛发生人次和使用强止痛药次数。结果 Ⅱ组病人的胸痛发生人次和使用强止痛药次数明显少于Ⅰ组(P均<0.01)。结论 提示硝酸甘油加肝素联合静点对急性心肌梗死病人具有较好的止痛作用,且可减少强止痛药物的用量。
Objective To observe the analgesic effects of nitroglycerin and heparin on acute myocardial infarction. Methods 553 patients with acute myocardial infarction were randomly divided into two groups: nitroglycerin alone group (Ⅰ) and nitroglycerin plus heparin group (Ⅱ), within 6h, 7h ~ 12h, 13h ~ 24h after treatment Patient’s chest pain occurred times and the use of strong painkiller times. Results The incidence of chest pain and use of strong analgesics in group Ⅱ were significantly less than those in group Ⅰ (all P <0.01). Conclusions Nitroglycerin plus heparin combined with intravenous point on patients with acute myocardial infarction has a good analgesic effect, and can reduce the amount of strong analgesic drugs.