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东茛菪碱是从中药洋金花内提取出来的生物碱,其镇静催眠及麻醉作用早已为人知,但临床上用于治疗失眠的资料极少。目前临床所用药物莨菪浸膏片,其主要成分就是东茛菪碱。本文对照观察了失眠患者服用莨菪浸膏片及安定的情况,以期对两种药物的疗效及异同作出初步研究。 1 资料和方法 1.1 资料 本院门诊于1992年1月至1994年6月间就诊的失眠病人,经临床化验及其它特殊检查符合神经衰弱诊断标准者69例。其中:男性28例,女性41例,平均年龄42岁,病程在1月~1年不等。 1.2 方法及有效判定 将69例失眠病人随机分成两组。实验组35例,服用莨菪浸膏片150mg,每日三次;对照组34例,服用安定5.0mg,每晚一次。疗程均为一周。对比疗程结束时及疗程结束后一周时失眠的缓解情况。
Scopolamine is an alkaloid extracted from the Chinese medicinal herbs, its sedative, hypnotic and anesthetic effects have long been known, but very little clinical information for the treatment of insomnia. At present, the clinical drug anisodine extract tablets, the main component is scopolamine. In this paper, we observed the insomnia patients taking the testosterone extract tablets and stability, in order to make a preliminary study of the efficacy and similarities and differences between the two drugs. 1 Materials and Methods 1.1 Materials In our hospital from January 1992 to June 1994 for treatment of insomnia patients, clinical laboratory tests and other special check meet the neurasthenic diagnostic criteria in 69 cases. Among them: 28 males and 41 females, with an average age of 42 years, ranging in duration from January to January. 1.2 methods and effective determination 69 cases of insomnia patients were randomly divided into two groups. In the experimental group, 35 cases were given 150mg of the testosterone extract tablets three times a day. In the control group, 34 cases were given Diazepam 5.0mg once a night. The course of treatment is one week. Comparison of treatment at the end of the course of treatment and insomnia a week after the relief.