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为观察糖尿病母亲的婴儿(IDMS)生长发有状况及探讨IDMs与糖尿病的相关性.方法对33例IDMs进行定期体格发育随访和智商(IQ)测定及家系调查.结果(1)体格发育及IQ处于正常范围;(2)检出糖尿病患儿(女,9.9岁)1例,患病率为3.03%;(3)31个家系中糖尿病家族史阳性家系21个,占66.7% 结论 IDMs糖尿病患病风险高于群体,其遗传背景与糖尿病患儿显示一致性.强调对IDMs远期随访及优育宣教尤其是多代连续造传的家系,有益于IDMs的健康成长及防治糖尿病.
To investigate the status of growth and development of IDMS in infants with diabetic mellitus (DM) and explore the relationship between IDMs and diabetes.Methods 33 IDMs were followed up for regular physical development and IQ test and pedigree investigation.Results (1) Physical development and IQ In the normal range; (2) detected in children with diabetes (female, 9.9 years old) in 1 case, the prevalence was 3.03%; (3) 21 families with positive family history of diabetes in 21 pedigrees, accounting for 66.7% The risk of disease is higher than that of the population, and its genetic background shows consistency with that of children with diabetes.It emphasizes the long-term follow-up of IDMs and education of maternity education, especially the multi-generational succession pedigree, which is beneficial to the healthy growth of IDMs and prevention and treatment of diabetes.